Last Updated: June 8, 2026

Patent: 10,450,361

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Summary for Patent: 10,450,361

Title:	Methods related to CTLA4-Fc fusion proteins
Abstract:	The present disclosure provides, in part, methods for evaluating, identifying, and/or producing (e.g., manufacturing) a CTLA4-Fc fusion protein, e.g., abatacept. In some instances, methods herein allow highly resolved evaluation of abatacept useful for, inter alia, manufacturing abatacept, characterizing abatacept, identifying and/or confirming abatacept, monitoring the structure of abatacept, comparing abatacept preparations made over time or made under different conditions, and/or controlling the structure of abatacept.
Inventor(s):	Robblee; John (Cambridge, MA), He; Xiaomei (Cambridge, MA), Yin; Yan (Cambridge, MA), Lin; Yin Yin (Cambridge, MA), Collins; Brian (Cambridge, MA), Murphy; Jennifer (Cambridge, MA), Kaundinya; Ganesh (Cambridge, MA)
Assignee:	Momenta Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:	14/404,939
Patent Claims:	see list of patent claims

Details for Patent 10,450,361

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bristol-myers Squibb Company	ORENCIA	abatacept	For Injection	125118	December 23, 2005	10,450,361	2033-05-31
Bristol-myers Squibb Company	ORENCIA	abatacept	Injection	125118	July 29, 2011	10,450,361	2033-05-31
Bristol-myers Squibb Company	ORENCIA	abatacept	Injection	125118	June 07, 2016	10,450,361	2033-05-31
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,450,361

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Country	Patent Number	Estimated Expiration
European Patent Office	2855533	⤷ Start Trial
United States of America	2015368317	⤷ Start Trial
World Intellectual Property Organization (WIPO)	2014149067	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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