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Patent: 10,322,162

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Summary for Patent: 10,322,162

Title:	Methods and pharmaceutical compositions for the treatment of ischemic conditions
Abstract:	The present invention relates to methods and pharmaceutical compositions for the treatment of ischemic conditions. In particular, the present invention relates to a method of treating an ischemic condition in a subject in need thereof comprising administering the subject with a polypeptide comprising an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino acid residue at position 186 to the amino acid residue at position 406 in SEQ ID NO: 1.
Inventor(s):	Germain; Stephane (Paris, FR), Berdeaux; Alain (Creteil, FR), Tissier; Renaud (Creteil, FR), Ghaleh-Marzban; Bijan (Creteil, FR), Monnot; Catherine (Paris, FR), Galaup; Ariane (Paris, FR)
Assignee:	INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (Paris, FR) COLLEGE DE FRANCE (Paris, FR) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Creteil, FR) UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE (Creteil, FR) ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP) (Paris, FR) ECOLE NATIONALE VETERINAIRE D\'ALFORT (ENVA) (Maisons-Alfort, FR)
Application Number:	15/541,422
Patent Claims:	see list of patent claims

Details for Patent 10,322,162

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Estimated Patent Expiration	Status	Orphan	Source
Ekr Therap	RETAVASE	reteplase	VIAL	103786	001	1998-05-06		INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (Paris, FR) COLLEGE DE FRANCE (Paris, FR) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Creteil, FR) UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE (Creteil, FR) ASSI	2035-01-06	RX		search
Genentech	CATHFLO ACTIVASE	alteplase	VIAL	103172	003	1987-11-13		INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (Paris, FR) COLLEGE DE FRANCE (Paris, FR) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Creteil, FR) UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE (Creteil, FR) ASSI	2035-01-06	RX		search
Genentech	ACTIVASE	alteplase	VIAL; SINGLE-USE	103172	002	1987-11-13		INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (Paris, FR) COLLEGE DE FRANCE (Paris, FR) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Creteil, FR) UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE (Creteil, FR) ASSI	2035-01-06	RX		search
Genentech	ACTIVASE	alteplase	VIAL; SINGLE-USE	103172	001	1987-11-13		INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (Paris, FR) COLLEGE DE FRANCE (Paris, FR) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Creteil, FR) UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE (Creteil, FR) ASSI	2035-01-06	RX		search
Microbix Biosystems	KINLYTIC	urokinase	INJECTABLE;INJECTION	021846	003	1978-01-16		INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (Paris, FR) COLLEGE DE FRANCE (Paris, FR) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Creteil, FR) UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE (Creteil, FR) ASSI	2035-01-06	DISCN		search
Microbix Biosystems	KINLYTIC	urokinase	INJECTABLE;INJECTION	021846	002	1978-01-16		INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (Paris, FR) COLLEGE DE FRANCE (Paris, FR) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (Creteil, FR) UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE (Creteil, FR) ASSI	2035-01-06	DISCN		search