Patent: 10,251,957
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Summary for Patent: 10,251,957
Title: | Composition for treating diabetes comprising long-acting insulin conjugate and long-acting insulinotropic peptide conjugate |
Abstract: | The present invention relates to a composition for the prevention or treatment of diabetes comprising a long-acting insulin conjugate and a long-acting insulinotropic peptide conjugate, and a therapeutic method for the treatment of diabetes, and more particularly, concurrent administration of the long-acting insulin conjugate and the long-acting insulinotropic peptide conjugate inhibits weight gain caused by insulin treatment, and vomiting and nausea caused by insulinotropic peptide treatment, and reduces the required dose of insulin, thereby remarkably improving drug compliance. Moreover, each of the long-acting insulin conjugate and the long-acting insulinotropic peptide conjugate of the present invention is prepared by linking insulin or insulinotropic peptide with an immunoglobulin Fc region via a non-peptidyl linker, thereby showing improved in-vivo duration of efficacy and stability. |
Inventor(s): | Woo; Young Eun (Daejeon, KR), Jang; Myung Hyun (Seoul, KR), Park; Young Jin (Suwon-si, KR), Park; Young Kyung (Hwaseong-si, KR), Lim; Chang Ki (Hwaseong-si, KR), Kwon; Se Chang (Seoul, KR) |
Assignee: | HANMI SCIENCE CO., LTD. (Hwaseong-si, KR) |
Application Number: | 14/123,355 |
Patent Claims: | see list of patent claims |
Details for Patent 10,251,957
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Sanofi-aventis U.s. Llc | LANTUS | insulin glargine | Injection | 021081 | 04/20/2000 | ⤷ Try a Trial | 2031-06-02 |
Sanofi-aventis U.s. Llc | LANTUS | insulin glargine | Injection | 021081 | 04/25/2007 | ⤷ Try a Trial | 2031-06-02 |
Novo Nordisk Inc. | LEVEMIR | insulin detemir | Injection | 021536 | 06/16/2005 | ⤷ Try a Trial | 2031-06-02 |
Novo Nordisk Inc. | LEVEMIR | insulin detemir | Injection | 021536 | 10/31/2013 | ⤷ Try a Trial | 2031-06-02 |
Eli Lilly And Company | BASAGLAR | insulin glargine | Injection | 205692 | 12/16/2015 | ⤷ Try a Trial | 2031-06-02 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |