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Last Updated: March 28, 2024

Patent: 10,251,957


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Summary for Patent: 10,251,957
Title:Composition for treating diabetes comprising long-acting insulin conjugate and long-acting insulinotropic peptide conjugate
Abstract: The present invention relates to a composition for the prevention or treatment of diabetes comprising a long-acting insulin conjugate and a long-acting insulinotropic peptide conjugate, and a therapeutic method for the treatment of diabetes, and more particularly, concurrent administration of the long-acting insulin conjugate and the long-acting insulinotropic peptide conjugate inhibits weight gain caused by insulin treatment, and vomiting and nausea caused by insulinotropic peptide treatment, and reduces the required dose of insulin, thereby remarkably improving drug compliance. Moreover, each of the long-acting insulin conjugate and the long-acting insulinotropic peptide conjugate of the present invention is prepared by linking insulin or insulinotropic peptide with an immunoglobulin Fc region via a non-peptidyl linker, thereby showing improved in-vivo duration of efficacy and stability.
Inventor(s): Woo; Young Eun (Daejeon, KR), Jang; Myung Hyun (Seoul, KR), Park; Young Jin (Suwon-si, KR), Park; Young Kyung (Hwaseong-si, KR), Lim; Chang Ki (Hwaseong-si, KR), Kwon; Se Chang (Seoul, KR)
Assignee: HANMI SCIENCE CO., LTD. (Hwaseong-si, KR)
Application Number:14/123,355
Patent Claims:see list of patent claims

Details for Patent 10,251,957

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Sanofi-aventis U.s. Llc LANTUS insulin glargine Injection 021081 04/20/2000 ⤷  Try a Trial 2031-06-02
Sanofi-aventis U.s. Llc LANTUS insulin glargine Injection 021081 04/25/2007 ⤷  Try a Trial 2031-06-02
Novo Nordisk Inc. LEVEMIR insulin detemir Injection 021536 06/16/2005 ⤷  Try a Trial 2031-06-02
Novo Nordisk Inc. LEVEMIR insulin detemir Injection 021536 10/31/2013 ⤷  Try a Trial 2031-06-02
Eli Lilly And Company BASAGLAR insulin glargine Injection 205692 12/16/2015 ⤷  Try a Trial 2031-06-02
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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