Last Updated: June 25, 2026

Patent: 10,233,245

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Summary for Patent: 10,233,245

Title:	Methods of treating inflammatory and autoimmune diseases with natalizumab
Abstract:	Natalizumab is a safe and efficacious treatment for inflammatory and autoimmune diseases, such as multiple sclerosis, Crohn\'s Disease, and rheumatoid arthritis. Rare occurrences of progressive multifocal leucoencephalopathy during treatment suggest the possibility that it may be related to natalizumab treatment. Monitoring for JCV and informing caregivers and patients about the manifestations of progressive multifocal leucoencephalopathy can improve the safety of natalizumab therapy.
Inventor(s):	Lieberburg; Ivan (Berkeley, CA)
Assignee:	BIOGEN MA INC. (Cambridge, MA)
Application Number:	15/596,468
Patent Claims:	see list of patent claims

Details for Patent 10,233,245

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	November 23, 2004	⤷ Start Trial	2037-05-16
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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