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Last Updated: September 21, 2020

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Patent: 10,221,140

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Summary for Patent: 10,221,140
Title:Asymmetric bisaminoquinolines and bisaminoquinolines with varied linkers as autophagy inhibitors for cancer and other therapy
Abstract: The invention provides novel asymmetric and symmetric bisaminoquinolmes and related compounds, methods of treatment and syntheses. The novel compounds exhibit effective anticancer activity and are useful in the treatment of a variety of autophagy-related disorders.
Inventor(s): Amaravadi; Ravi K. (Media, PA), Winkler; Jeffrey (Wynnewood, PA)
Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, PA)
Application Number:15/502,330
Patent Claims:see list of patent claims

Details for Patent 10,221,140

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, PA) 2034-08-08 RX search
Organon Usa Inc. TICE BCG bacillus calmette-guerin POWDER, FOR SUSPENSION 102821 1 1990-08-24   Start Trial THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, PA) 2034-08-08 search
Organon Usa Inc. BCG VACCINE bacillus calmette-guerin substrain tice live antigen INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 103050 1 1989-06-21   Start Trial THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, PA) 2034-08-08 search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, PA) 2034-08-08 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, PA) 2034-08-08 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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