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Last Updated: April 19, 2024

Patent: 10,221,140

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Summary for Patent: 10,221,140

Title:	Asymmetric bisaminoquinolines and bisaminoquinolines with varied linkers as autophagy inhibitors for cancer and other therapy
Abstract:	The invention provides novel asymmetric and symmetric bisaminoquinolmes and related compounds, methods of treatment and syntheses. The novel compounds exhibit effective anticancer activity and are useful in the treatment of a variety of autophagy-related disorders.
Inventor(s):	Amaravadi; Ravi K. (Media, PA), Winkler; Jeffrey (Wynnewood, PA)
Assignee:	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, PA)
Application Number:	15/502,330
Patent Claims:	see list of patent claims

Details for Patent 10,221,140

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Recordati Rare Diseases, Inc.	ELSPAR	asparaginase	For Injection	101063	01/10/1978	⤷ Try a Trial	2034-08-08
Merck Teknika Llc	TICE BCG	bcg live	For Injection	102821	06/21/1989	⤷ Try a Trial	2034-08-08
Merck Teknika Llc	N/A	bcg vaccine	For Injection	103050	06/21/1989	⤷ Try a Trial	2034-08-08
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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