Last Updated: July 10, 2026

Patent: 10,214,585

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Summary for Patent: 10,214,585

Title:	Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
Abstract:	A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a disease, disorder, condition or injury of the CNS that does not include the autoimmune neuroinflammatory disease, relapsing-remitting multiple sclerosis (RRMS), is provided. The pharmaceutical composition is for administration by a dosage regimen comprising at least two courses of therapy, each course of therapy comprising in sequence a treatment session followed by an interval session of non-treatment.
Inventor(s):	Eisenbach-Schwartz; Michal (Rehovot, IL), Baruch; Kuti (Rehovot, IL), Rosenzweig; Neta (Rehovot, IL)
Assignee:	Yeda Research and Development Co., Ltd. (Rehovot, IL)
Application Number:	14/850,794
Patent Claims:	see list of patent claims

Details for Patent 10,214,585

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genentech, Inc.	TECENTRIQ	atezolizumab	Injection	761034	May 18, 2016	10,214,585	2035-09-10
Genentech, Inc.	TECENTRIQ	atezolizumab	Injection	761034	March 08, 2019	10,214,585	2035-09-10
Emd Serono, Inc.	BAVENCIO	avelumab	Injection	761049	March 23, 2017	10,214,585	2035-09-10
Astrazeneca Uk Ltd	IMFINZI	durvalumab	Injection	761069	May 01, 2017	10,214,585	2035-09-10
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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