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Last Updated: December 15, 2019

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Patent: 10,143,723

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Summary for Patent: 10,143,723
Title:Methods of using OX40 ligand encoding polynucleotides
Abstract: The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules comprising an mRNA encoding an OX40L polypeptide. Also provided is a method for activating T cells or increasing the number of NK cells in a subject in need thereof.
Inventor(s): Frederick; Joshua P. (Boston, MA), Bai; Ailin (Newton, MA)
Assignee: ModernaTX, Inc. (Cambridge, MA)
Application Number:15/996,140
Patent Claims:see list of patent claims

Details for Patent 10,143,723

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Emd Serono Inc BAVENCIO avelumab INJECTABLE;INTRAVENOUS 761078 001 2017-05-09   Start Trial ModernaTX, Inc. (Cambridge, MA) 2035-12-23 RX search
Astrazeneca Uk Ltd IMFINZI durvalumab INJECTABLE;INJECTION 761069 001 2017-05-01   Start Trial ModernaTX, Inc. (Cambridge, MA) 2035-12-23 RX search
Emd Serono Inc BAVENCIO avelumab INJECTABLE;INJECTION 761049 001 2017-04-25   Start Trial ModernaTX, Inc. (Cambridge, MA) 2035-12-23 RX Orphan search
Genentech Inc TECENTRIQ atezolizumab INJECTABLE; INJECTION 761041 001 2016-10-18   Start Trial ModernaTX, Inc. (Cambridge, MA) 2035-12-23 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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