Patent: 10,124,056
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Summary for Patent: 10,124,056
Title: | Alkylated influenza vaccines |
Abstract: | The present invention provides, among other things, improved influenza vaccines based on hemagglutinins containing one or more alkylated cysteine residues. In particular, the present invention provides influenza vaccines containing hemagglutinins treated with an alkylating agent and methods of making the same. Inventive influenza vaccines provided by the present invention have a remarkable ability to retain potency as determined by Single Radial Immunodiffusion (SRID) assay upon storage. |
Inventor(s): | Milner; Brooke S. (Easton, PA), Haines; Jonathan (Effort, PA), Hauser; Steven L. (Easton, PA), Poli; Janet Beebe (Bethlehem, PA) |
Assignee: | Sanofi Pasteur Inc. (Swiftwater, PA) |
Application Number: | 14/829,158 |
Patent Claims: | see list of patent claims |