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Last Updated: September 21, 2020

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Patent: 10,100,106

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Summary for Patent: 10,100,106
Title:Single domain serum albumin binding protein
Abstract: Disclosed herein are single domain serum albumins binding proteins with improved thermal stability, binding affinities, and robust aggregation profiles. Also described are multispecific binding proteins comprising a single domain serum albumin binding protein according to the instant disclosure. Pharmaceutical compositions comprising the binding proteins disclosed herein and methods of using such formulations are provided.
Inventor(s): Dubridge; Robert B. (Belmont, CA), Lemon; Bryan D. (Mountain View, CA), Austin; Richard J. (San Francisco, CA), Evnin; Luke (San Francisco, CA), Guenot; Jeanmarie (San Francisco, CA)
Assignee: HARPOON THERAPEUTICS, INC. (South San Francisco, CA)
Application Number:15/600,582
Patent Claims:see list of patent claims

Details for Patent 10,100,106

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial HARPOON THERAPEUTICS, INC. (South San Francisco, CA) 2036-05-20 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial HARPOON THERAPEUTICS, INC. (South San Francisco, CA) 2036-05-20 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial HARPOON THERAPEUTICS, INC. (South San Francisco, CA) 2036-05-20 search
Grifols Usa, Llc ALBUTEIN albumin (human) INJECTION, SOLUTION 102478 1 2019-12-15   Start Trial HARPOON THERAPEUTICS, INC. (South San Francisco, CA) 2036-05-20 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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