Patent: 10,087,251
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Summary for Patent: 10,087,251
| Title: | Amino acid sequences that modulate the interaction between cells of the immune system |
| Abstract: | The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as \"APC target\") or a target on a T-cell (also referred to herein as \"T-cell target\"). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. |
| Inventor(s): | Hermans; Guy (Merelbeke, BE), Verheesen; Peter (Gent, BE), Dolk; Edward (Utrecht, NL), Hoogenboom; Hendricus Renerus Jacobus Mattheus (Maastricht, NL), Saunders; Michael John Scott (Brussels, BE), De Haard; Hans (Oudelande, NL), de Bruin; Renee (Amsterdam, NL) |
| Assignee: | Ablynx N.V. (Ghent-Zwijnaarde, BE) |
| Application Number: | 15/050,737 |
| Patent Claims: | see list of patent claims |
Details for Patent 10,087,251
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Grifols Therapeutics Llc | ALBUKED, PLASBUMIN-20, PLASBUMIN-25, PLASBUMIN-5 | albumin (human) | For Injection | 101138 | 10/21/1942 | ⤷ Try a Trial | 2026-12-15 |
| Baxalta Us Inc. | BUMINATE, FLEXBUMIN | albumin (human) | Injection | 101452 | 03/03/1954 | ⤷ Try a Trial | 2026-12-15 |
| Csl Behring Ag | ALBURX | albumin (human) | Injection | 102366 | 07/23/1976 | ⤷ Try a Trial | 2026-12-15 |
| Grifols Biologicals Llc | ALBUTEIN | albumin (human) | Injection | 102478 | 08/15/1978 | ⤷ Try a Trial | 2026-12-15 |
| Instituto Grifols, S.a. | HUMAN ALBUMIN GRIFOLS | albumin (human) | Injection | 103352 | 02/17/1995 | ⤷ Try a Trial | 2026-12-15 |
| Instituto Grifols, S.a. | HUMAN ALBUMIN GRIFOLS | albumin (human) | Injection | 103352 | 06/11/2003 | ⤷ Try a Trial | 2026-12-15 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
