Patent: 10,081,657
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Summary for Patent: 10,081,657
Title: | Biosynthetic proline/alanine random coil polypeptides and their uses |
Abstract: | The present invention relates to a biosynthetic random coil polypeptide or a biosynthetic random coil polypeptide segment or biosynthetic conjugate, in which the biosynthetic random coil polypeptide, the biosynthetic random coil polypeptide segment, or the biosynthetic conjugate comprises an amino acid sequence consisting solely of proline and alanine amino acid residues, wherein the amino acid sequence consists of at least about 50 proline (Pro) and alanine (Ala) amino acid residues. The at least about 50 proline (Pro) and alanine (Ala) amino acid residues may be (a) constituent(s) of a heterologous polypeptide or an heterologous polypeptide construct. Also uses and methods of use of these biosynthetic random coil polypeptides or polypeptide segments or conjugates are described. |
Inventor(s): | Skerra; Arne (Freising, DE), Binder; Uli (Freising, DE), Schlapschy; Martin (Freising, DE) |
Assignee: | TECHNISCHE UNIVERSITAT MUNCHEN (Munich, DE) XL-PROTEIN GMBH (Freising, DE) |
Application Number: | 14/939,626 |
Patent Claims: | see list of patent claims |
Details for Patent 10,081,657
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Bausch & Lomb Incorporated | VITRASE | hyaluronidase | Injection | 021640 | 05/05/2004 | ⤷ Try a Trial | 2030-05-21 |
Bausch & Lomb Incorporated | VITRASE | hyaluronidase | Injection | 021640 | 12/02/2004 | ⤷ Try a Trial | 2030-05-21 |
Amphastar Pharmaceuticals, Inc. | AMPHADASE | hyaluronidase | Injection | 021665 | 10/26/2004 | ⤷ Try a Trial | 2030-05-21 |
Akorn, Inc. | HYDASE | hyaluronidase | Injection | 021716 | 10/25/2005 | ⤷ Try a Trial | 2030-05-21 |
Chiesi Usa, Inc. | RETAVASE | reteplase | For Injection | 103786 | 10/30/1996 | ⤷ Try a Trial | 2030-05-21 |
Swedish Orphan Biovitrum Ab (publ) | KINERET | anakinra | Injection | 103950 | 11/14/2001 | ⤷ Try a Trial | 2030-05-21 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |