Patent: 10,081,657

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Summary for Patent: 10,081,657

Title:	Biosynthetic proline/alanine random coil polypeptides and their uses
Abstract:	The present invention relates to a biosynthetic random coil polypeptide or a biosynthetic random coil polypeptide segment or biosynthetic conjugate, in which the biosynthetic random coil polypeptide, the biosynthetic random coil polypeptide segment, or the biosynthetic conjugate comprises an amino acid sequence consisting solely of proline and alanine amino acid residues, wherein the amino acid sequence consists of at least about 50 proline (Pro) and alanine (Ala) amino acid residues. The at least about 50 proline (Pro) and alanine (Ala) amino acid residues may be (a) constituent(s) of a heterologous polypeptide or an heterologous polypeptide construct. Also uses and methods of use of these biosynthetic random coil polypeptides or polypeptide segments or conjugates are described.
Inventor(s):	Skerra; Arne (Freising, DE), Binder; Uli (Freising, DE), Schlapschy; Martin (Freising, DE)
Assignee:	TECHNISCHE UNIVERSITAT MUNCHEN (Munich, DE) XL-PROTEIN GMBH (Freising, DE)
Application Number:	14/939,626
Patent Claims:	see list of patent claims

Details for Patent 10,081,657

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Bausch & Lomb Incorporated	VITRASE	hyaluronidase	Injection	021640	05/05/2004	See Plans and Pricing	2030-05-21
Bausch & Lomb Incorporated	VITRASE	hyaluronidase	Injection	021640	12/02/2004	See Plans and Pricing	2030-05-21
Amphastar Pharmaceuticals, Inc.	AMPHADASE	hyaluronidase	Injection	021665	10/26/2004	See Plans and Pricing	2030-05-21
Akorn, Inc.	HYDASE	hyaluronidase	Injection	021716	10/25/2005	See Plans and Pricing	2030-05-21
Chiesi Usa, Inc.	RETAVASE	reteplase	For Injection	103786	10/30/1996	See Plans and Pricing	2030-05-21
Swedish Orphan Biovitrum Ab (publ)	KINERET	anakinra	Injection	103950	11/14/2001	See Plans and Pricing	2030-05-21
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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