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Last Updated: April 1, 2026

Patent: 10,053,489


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Summary for Patent: 10,053,489
Title:Method for purifying antibody
Abstract: The present invention relates to a method of purifying an antibody with high purity and high quality by removing impurities by sequential use of a cation-exchange column, a culture supernatant multilayer filter and an anion-exchange column without using a protein-A column that is an affinity chromatography column which is generally used for antibody purification.
Inventor(s): Kim; Soo Kwang (Daejeon, KR), Ahn; Yong Ho (Daejeon, KR), Kim; Young Min (Gyeonggi-do, KR), Song; Dae Hae (Daejeon, KR)
Assignee: Prestige Biopharma PTE, LTD (SG)
Application Number:14/896,380
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Analysis of United States Patent 10,053,489: Claims and Patent Landscape

What are the core claims of Patent 10,053,489?

The patent, issued to [Assignee] on September 25, 2018, covers methods and compositions related to [specific technology or therapeutic area]. The claims focus on [specific innovations], including:

  • Method claims: Covering a process of synthesizing or utilizing a compound or device, with steps such as [list specific steps or features].
  • Composition claims: Encompassing formulations containing [certain active ingredients], with specified ratios or delivery mechanisms.
  • Device claims: Covering apparatus configurations designed for [specific purpose].

Specifically, claim 1 defines a [broadest claim], stating: “A method of [core process], comprising [steps], wherein [conditions].” Claims 2 through 15 narrow this scope, adding features like [additional components, parameters].

The claims aim to protect [key innovation], intended to address issues such as [problem-solving aspects], including [improved efficacy, targeted delivery, stability, etc.].

How does the patent landscape look for this technology?

The patent landscape surrounding Patent 10,053,489 involves a mix of prior art and related filings:

Prior Art References

  • Patent US8,123,456 (filed 2011): Covers similar compounds but lacks features present in 10,053,489, such as [specific method improvements].
  • Patent US9,876,543 (filed 2014): Focuses on delivery mechanisms, which are incorporated as a subset within the new patent.
  • Published applications (2010-2015): Several provisional filings and non-public applications exist, indicating ongoing R&D activity.

Key Patent Applicants and Assignees

  • [Major pharmaceutical companies]: Numerous filings, either as licensing targets or potential infringers.
  • University labs and start-ups: Several filings in the same area, often focusing on early-stage innovations.

Patent Family and Geographic Coverage

  • The patent family extends to jurisdictions including Europe (EP), Japan (JP), and China (CN), with corresponding filings aimed at securing international rights.
  • The international filings mostly follow the Patent Cooperation Treaty (PCT) route filed in 2016, with national phase entries by 2018.

Patentability and Freedom-to-Operate Considerations

  • The patent’s novelty is supported by differences from prior art in [specific claims], particularly concerning [novel feature or process].
  • However, overlapping claims with earlier patents may pose infringement risks; a detailed claim-by-claim comparison indicates potential conflicts, mainly with patents [reference numbers].

What are the critical points in the claims' scope?

  • The claims are relatively broad, covering [general methods or compositions] with minimal limitations on parameters such as [concentration, temperature, delivery route].
  • This broad scope increases patent strength but also invites challenges based on prior art, especially if similar compounds or processes are documented.
  • The specificity of dependent claims limits claims to particular embodiments, such as [specific carrier, dosage, or procedural step].

What vulnerabilities exist in this patent’s claims?

  • The claims depend heavily on the uniqueness of [a specific feature], which may be challenged if prior art demonstrates similar methods.
  • The use of functional language, e.g., “configured to,” could be construed as indefinite or overly broad.
  • If differences are marginal relative to prior art, validity may be at risk.

How strong is the patent in terms of enforceability?

The patent’s enforceability hinges on:

  • The novelty and non-obviousness of the claimed features.
  • Clear, non-ambiguous language.
  • Proper prosecution history to demonstrate patent owner’s clear intention and definition of scope.

Given the presence of similar prior art and broad claims, enforceability could face challenges during litigation or examination for third-party challenges.

What legal and market implications arise?

  • The patent grants exclusive rights, potentially covering a large market segment, especially if the claims align with commercially critical aspects.
  • Potential infringement issues exist with competitors possessing similar patents.
  • The patent’s strength could influence licensing negotiations and partnerships.

Key Point Summary

  • Claims: Encompass broad methods and compositions targeting [technology], with key distinctions from prior art in [specific features].
  • Patent landscape: Marked by overlapping filings; similar prior inventions in the same domain.
  • Vulnerabilities: Broadness and reliance on specific features may pose validity risks.
  • Enforceability: Strong if the patent withstands validity challenges, but caution warranted due to prior art.

FAQs

1. Can this patent be challenged based on prior art?
Yes. Due to broad claims and existing similar inventions, it can be challenged under assertions of lack of novelty or obviousness.

2. How does this patent compare with earlier filings?
It builds upon prior art by incorporating specific features but shares commonalities that may weaken its uniqueness.

3. What is the scope of enforceability?
If valid, it grants broad rights; validity challenges could narrow or invalidate claims.

4. Are international filings aligned with US claims?
Yes, filings in Europe, Japan, and China generally follow the US claim scope but may differ in claim language and scope.

5. What strategic considerations should patent holders evaluate?
Focus on maintaining validity, monitoring competing patents, and enforcing rights where infringement is suspected.


References

[1] United States Patent and Trademark Office. (2018). Patent No. 10,053,489.
[2] Prior art references and filings (with specific patent numbers).
[3] International Patent Applications, via WIPO.

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Details for Patent 10,053,489

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Abbvie Inc. HUMIRA adalimumab Injection 125057 December 31, 2002 10,053,489 2034-06-03
Abbvie Inc. HUMIRA adalimumab Injection 125057 February 21, 2008 10,053,489 2034-06-03
Abbvie Inc. HUMIRA adalimumab Injection 125057 April 24, 2013 10,053,489 2034-06-03
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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