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Last Updated: September 27, 2020

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Patent: 10,052,345

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Summary for Patent: 10,052,345
Title:Assays, methods and kits for predicting renal disease and personalized treatment strategies
Abstract: Assays, methods and kits for predicting a subject\'s (e.g., human) risk of primary glomerulopathy, secondary glomerulopathy or recurrence (e.g., post-transplant recurrence) of any glomerular disease include examining cells for the presence or absence of cytoskeletal disruptions or rearrangements and examining cells for modulation of expression and/or activity of markers such as SMPDL-3b. Assays for predicting if a diabetic subject will develop kidney disease or a patient with FSGS will develop recurrent disease after transplant also include examining cells for the presence or absence of cytoskeletal disruptions or rearrangements and examining cells for modulation of expression and/or activity of markers such as SMPDL-3b. Also described herein are compositions and methods for treating and preventing the afore-mentioned disorders.
Inventor(s): Fornoni; Alessia (Coral Gables, FL), Burke; George William (Miami, FL), Merscher-Gomez; Sandra (Miami, FL)
Assignee: University of Miami (Miami, FL)
Application Number:13/879,892
Patent Claims:see list of patent claims

Details for Patent 10,052,345

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bristol Myers Squibb ORENCIA abatacept INJECTABLE; IV (INFUSION) 125118 001 2005-12-23   Start Trial University of Miami (Miami, FL) 2030-10-19 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Merck
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Mallinckrodt
Medtronic
Harvard Business School
Dow

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