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Last Updated: March 29, 2024

Patent: 10,052,345


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Summary for Patent: 10,052,345
Title:Assays, methods and kits for predicting renal disease and personalized treatment strategies
Abstract: Assays, methods and kits for predicting a subject\'s (e.g., human) risk of primary glomerulopathy, secondary glomerulopathy or recurrence (e.g., post-transplant recurrence) of any glomerular disease include examining cells for the presence or absence of cytoskeletal disruptions or rearrangements and examining cells for modulation of expression and/or activity of markers such as SMPDL-3b. Assays for predicting if a diabetic subject will develop kidney disease or a patient with FSGS will develop recurrent disease after transplant also include examining cells for the presence or absence of cytoskeletal disruptions or rearrangements and examining cells for modulation of expression and/or activity of markers such as SMPDL-3b. Also described herein are compositions and methods for treating and preventing the afore-mentioned disorders.
Inventor(s): Fornoni; Alessia (Coral Gables, FL), Burke; George William (Miami, FL), Merscher-Gomez; Sandra (Miami, FL)
Assignee: University of Miami (Miami, FL)
Application Number:13/879,892
Patent Claims:see list of patent claims

Details for Patent 10,052,345

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bristol-myers Squibb Company ORENCIA abatacept For Injection 125118 12/23/2005 ⤷  Try a Trial 2030-10-19
Bristol-myers Squibb Company ORENCIA abatacept Injection 125118 07/29/2011 ⤷  Try a Trial 2030-10-19
Bristol-myers Squibb Company ORENCIA abatacept Injection 125118 06/07/2016 ⤷  Try a Trial 2030-10-19
Bristol-myers Squibb Company ORENCIA abatacept Injection 125118 03/30/2017 ⤷  Try a Trial 2030-10-19
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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