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Last Updated: September 22, 2020

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Patent: 10,047,096

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Summary for Patent: 10,047,096
Title:Substituted pyridobenzodiazepinone-derivatives and use thereof
Abstract: The present application relates to novel (3-hydroxyphenyl)amino-substituted pyrido[2,3-b][1,5]benzodiazepin-5-one derivatives, to processes for preparation thereof, to the use thereof alone or in combination for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially of angiogenic disorders and hyperproliferative disorders in which neovascularization plays a role, for example ophthalmological disorders and cancers and tumours. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.
Inventor(s): Schall; Andreas (Wuppertal, DE), Klar; Jurgen (Wuppertal, DE), Lobell; Mario (Wuppertal, DE), Schirok; Hartmut (Langenfeld, DE), Telser; Joachim (Wuppertal, DE), Muller; Steffen (Essen, DE), Brohm; Dirk (Mettmann, DE), Briem; Hans (Berlin, DE), Jori en; Hannah (Heiligenhaus, DE), Keldenich; Joerg (Berlin, DE), Bottger; Michael (Wuppertal, DE), Von Degenfeld; Georges (Leverkusen, DE), Schlange; Thomas (Haan, DE), Bomer; Ulf (Glienicke, DE), Lindner; Niels (Wuppertal, DE), Eilken; Hanna (Wuppertal, DE), Hristodorov; Dmitrij (Wuppertal, DE), Wasnaire; Pierre (Dusseldorf, DE), Gericke; Kersten Matthias (Wuppertal, DE), Barfacker; Lars (Dusseldorf, DE)
Assignee: Bayer Pharma Aktiengesellschaft (Berlin, DE)
Application Number:15/529,043
Patent Claims:see list of patent claims

Details for Patent 10,047,096

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Start Trial Bayer Pharma Aktiengesellschaft (Berlin, DE) 2034-11-25 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26   Start Trial Bayer Pharma Aktiengesellschaft (Berlin, DE) 2034-11-25 RX Orphan search
Genentech LUCENTIS ranibizumab INJECTABLE; INJECTION 125156 001 2006-06-30   Start Trial Bayer Pharma Aktiengesellschaft (Berlin, DE) 2034-11-25 RX search
Regeneron Pharmaceuticals EYLEA aflibercept INJECTABLE; INJECTION 125387 001 2011-11-18   Start Trial Bayer Pharma Aktiengesellschaft (Berlin, DE) 2034-11-25 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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