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Last Updated: September 17, 2021

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Patent: 10,040,855

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Summary for Patent: 10,040,855
Title:Formulation for anti-.alpha.4.beta.7 antibody
Abstract: Antibody formulations are described comprising a mixture of an anti-.alpha.4.beta.7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-.alpha.4.beta.7 antibody in vivo.
Inventor(s): Diluzio; Willow (Westford, MA), Nguyen; Phoung M. (Cambridge, MA), Varga; Csanad M. (Newton, MA), Palaniappan; Vaithianathan (Andover, MA), Brown; Jason (Burlington, MA)
Assignee: Millennium Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:14/114,835
Patent Claims:see list of patent claims

Details for Patent 10,040,855

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Takeda Pharms Usa ENTYVIO vedolizumab INJECTABLE;INJECTION 125476 001 2014-05-20 ⤷  Try it Free Millennium Pharmaceuticals, Inc. (Cambridge, MA) 2031-05-02 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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