Patent: 10,040,855
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Summary for Patent: 10,040,855
Title: | Formulation for anti-.alpha.4.beta.7 antibody |
Abstract: | Antibody formulations are described comprising a mixture of an anti-.alpha.4.beta.7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-.alpha.4.beta.7 antibody in vivo. |
Inventor(s): | Diluzio; Willow (Westford, MA), Nguyen; Phoung M. (Cambridge, MA), Varga; Csanad M. (Newton, MA), Palaniappan; Vaithianathan (Andover, MA), Brown; Jason (Burlington, MA) |
Assignee: | Millennium Pharmaceuticals, Inc. (Cambridge, MA) |
Application Number: | 14/114,835 |
Patent Claims: | see list of patent claims |
Details for Patent 10,040,855
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Takeda Pharmaceuticals U.s.a., Inc. | ENTYVIO | vedolizumab | For Injection | 125476 | 05/20/2014 | ⤷ Try a Trial | 2031-05-02 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |