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Last Updated: August 1, 2021

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Patent: 10,023,917

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Summary for Patent: 10,023,917
Title:High resolution melting analysis as a prescreening tool
Abstract: Compositions and methods for determining an increased likelihood of a response to a targeted treatment of a cancer disease including isolating genomic DNA from a patient sample, amplifying a fragment of DNA by means of PCR with a specific pair of amplification primers, determining if the amplified fragment comprises a wildtype sequence or a mutation by means of a High Resolution Melting Analysis (HRM), and correlating the presence or absence of a mutation with an increased likelihood of success of said targeted treatment. Respective primer pairs, compositions and kits are also claimed.
Inventor(s): Buettner; Reinhard (Villiprott, DE), Froehner; Stefanie (Penzberg, DE), Merkelbach-Bruse; Sabine (Aachen, DE), Ney; Jasmin (Wallerfangen, DE), Roesler; Angelika (Sindelsdorf, DE)
Assignee: Roche Molecular Systems, Inc. (Pleasanton, CA)
Application Number:14/958,567
Patent Claims:see list of patent claims

Details for Patent 10,023,917

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 003 2006-09-27 ⤷  Try it Free Roche Molecular Systems, Inc. (Pleasanton, CA) 2031-01-11 RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 002 2006-09-27 ⤷  Try it Free Roche Molecular Systems, Inc. (Pleasanton, CA) 2031-01-11 RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 001 2006-09-27 ⤷  Try it Free Roche Molecular Systems, Inc. (Pleasanton, CA) 2031-01-11 RX search
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18 ⤷  Try it Free Roche Molecular Systems, Inc. (Pleasanton, CA) 2031-01-11 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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