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Last Updated: October 6, 2022

Patent: 10,022,451


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Summary for Patent: 10,022,451
Title:Encapsulated agents and methods of making and using thereof
Abstract: The subject matter disclosed herein relates to compositions that contain a protein cage and a therapeutic agent, such as a photosensitizer. The protein cage is a protein that binds metal ion. The composition can further contain a cell recognition moiety. The methods disclosed are for permeabilizing the endothelial lining of a cancerous tissue or for treating a cancerous tissue to cause therapeutic injury resulting in the reduction of at least one of the surface area, the depth, and the amount of the tissue affected by the cancerous condition, in a subject.
Inventor(s): Xie; Jin (Athens, GA), Zhen; Zipeng (Athens, GA), Tang; Wei (Athens, GA)
Assignee: University of Georgia Research Foundation, Inc. (Athens, GA)
Application Number:14/709,090
Patent Claims:see list of patent claims

Details for Patent 10,022,451

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. RITUXAN rituximab Injection 103705 11/26/1997 See Plans and Pricing 2039-02-26
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 09/25/1998 See Plans and Pricing 2039-02-26
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 02/10/2017 See Plans and Pricing 2039-02-26
Genzyme Corporation CAMPATH alemtuzumab Injection 103948 05/07/2001 See Plans and Pricing 2039-02-26
Genzyme Corporation LEMTRADA alemtuzumab Injection 103948 11/14/2014 See Plans and Pricing 2039-02-26
Genzyme Corporation CAMPATH alemtuzumab Injection 103948 10/12/2004 See Plans and Pricing 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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