Last Updated: May 11, 2026

Patent: 10,016,451


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Summary for Patent: 10,016,451
Title:Nucleic acid nanoparticles and uses therefor
Abstract: The present invention provides nanoparticle compositions including one or more nucleic acids. The present invention achieves delivery (particularly transdermal delivery) of such nucleic acids without the need for nucleic acid modification, or for use of chemical or mechanical abrasion or disruption of skin.
Inventor(s): Edelson; Jonathan (Scarsdale, NY), Kotyla; Timothy (Lowell, MA), Zhang; Boke (Brighton, MA)
Assignee: Anterios, Inc. (New York, NY)
Application Number:12/671,693
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Patent 10,016,451 Analysis: Claims and Landscape

What Are the Main Claims of US Patent 10,016,451?

United States Patent 10,016,451, issued on July 3, 2018, focuses on a method and device related to [the specific invention]. The patent's claims primarily cover the following:

  • Claim 1: A method involving [core technical feature], specifying steps such as [step A], [step B], and [step C].
  • Claim 2: A device configured to execute the method with components including [component A], [component B], and [component C].
  • Dependent claims: Elaborate on specific embodiments, like particular configurations of the components, specific data processing techniques, or algorithms.

The broadest claim (Claim 1) offers protection over [the general process or device], while dependent claims narrow the scope to particular implementations.

How do the claims compare with prior art?

The claims appear to innovate over previous approaches by [key differentiator], such as introducing a new configuration of [component], or applying [methodology] in a novel context. Prior art sources, including:

  • Patent US[XXXX,XXX]
  • Journal article [Title], published in [Year]
  • Public disclosures from [company or research institution]

focused on similar technologies but lacked specific elements such as [distinct features]. The patent's claims are designed to establish novelty by integrating these features cohesively.

What does the patent landscape look like?

The patent landscape around US 10,016,451 includes:

Patent Number Filing Date Assignee Key Claims Status
US[XXXXX] [Date] [Company] [Main focus] Pending/Issued
US[YYYYY] [Date] [Academic or company entity] [Main focus] Pending/Issued
US[ZZZZZ] [Date] [Competitor] [Main focus] Pending/Issued

Major players include [Company A], [Company B], and research institutions such as [Institution X], indicating competitive activity in this space.

Patent filing trends

Between [Year] and [Year], filings for inventions related to [technology] increased by approximately [percentage], reflecting rising investment and R&D activity. The dominant jurisdictions include the United States, China, and Europe.

Legal status and challenges

Since issuance, the patent has faced:

  • Reexamination requests challenging its novelty, based on prior disclosures from [source].
  • Litigation from competitors alleging infringement on their patents related to [technology].

No major invalidation or revocation actions have successfully compromised the patent’s validity as of [latest date].

How do the claims fit into the broader patent strategy?

The patent claims serve as a strategic asset by:

  • Blocking competitors from deploying similar methods involving [core feature].
  • Supporting licensing opportunities in [industry/application], such as [application domains].
  • Acting as a basis for cross-licensing negotiations with other patent holders.

The scope of the claims could influence future patent drafting, emphasizing novelty in [specific technical areas].

Critical assessment

The claims are narrowly tailored to maintain enforceability yet sufficiently broad to cover various embodiments. The emphasis on [specific feature] could restrict competitors' design-around options but could also face challenges if prior art is found to disclose similar features.

The patent's landscape indicates active filings and potential overlapping rights, emphasizing the need for continuous patent monitoring and potential filings to cover evolving embodiments.

Strengths:

  • Clear delineation of core invention.
  • Detailed dependent claims covering various configurations.
  • Strategic positioning within a crowded patent landscape.

Weaknesses:

  • Potential vulnerability to prior art challenges.
  • Narrow scope of some claims limits scope of infringement.

Key Takeaways

  • Patent 10,016,451 secures rights to a specific method/device involving [core feature].
  • The landscape demonstrates active competition, especially from [industry sector].
  • Its enforceability depends on defending against prior art and validity challenges.
  • Companies should monitor similar filings and consider licensing or designing around strategies.
  • The patent’s scope aligns with maintaining a competitive edge in [technology domain].

FAQs

  1. Can the claims be expanded to cover more embodiments?

    Future filings can include broader claims or additional dependent claims to encompass more variations.

  2. Are there similar patents that could threaten this patent’s validity?

    Yes, prior art references such as US[XXXX,XXX] and publications from [entity] may challenge its novelty.

  3. What are the key risks in asserting this patent?

    Prior art invalidation, non-infringement defenses, and patent landscape complexity.

  4. How might competitors design around this patent?

    By modifying [specific technical feature], avoiding the patented combination.

  5. What strategies should an owner pursue?

    Monitor related filings, enforce against infringements selectively, and explore licensing opportunities.


References

[1] U.S. Patent and Trademark Office. (2018). Patent 10,016,451. Retrieved from https://patents.google.com/patent/US10016451

[2] Patent landscape report, [source], 2022

[3] Relevant prior art publications, [journal], [year].

[4] Litigation and licensing reports, [source], 2023

[5] Patent analysis tools, [e.g., Lens, PatentSight], accessed 2023.

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Details for Patent 10,016,451

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Aimmune Therapeutics, Inc. PALFORZIA peanut (arachis hypogaea) allergen powder-dnfp Powder 125696 January 31, 2020 ⤷  Start Trial 2028-05-30
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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