Histone deacetylase 6 inhibition for enhancing T-cell function during anti-tumor response and tumor-peptide vaccination
Disclosed are methods whereby an effective amount of a HDAC6 inhibitor is used to activate a subjects T-cell response to tumor or tumor vaccine. Methods of using HDAC6 inhibitors to increase a subjects anti-tumor immune response, alone or in conjunction with other tumor treatments, are also disclosed.
Sotomayor; Eduardo M. (Tampa, FL), Villagra; Alejandro V. (Tampa, FL)
H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, FL)
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