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Last Updated: December 28, 2025

Patent: 10,000,570


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Summary for Patent: 10,000,570
Title:Antibody variants having modifications in the constant region
Abstract:The present invention relates to positions in the constant region of antibodies, in particular the CH3 region of IgG4, which affect the strength of CH3-CH3 interactions. Mutations that either stabilize or destabilize this interaction are disclosed.
Inventor(s):Aran Frank Labrijn, Stefan Loverix, Paul Parren, Jan van de Winkel, Janine Schuurman, Ignace Lasters
Assignee: Genmab AS
Application Number:US14/739,768
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

United States Patent 10,000,570 (USP 10,000,570): A Comprehensive and Critical Analysis of Its Claims and Patent Landscape


Summary

United States Patent 10,000,570 (issued March 26, 2019) primarily covers novel methods and compositions related to [insert specific technology or field based on the patent]. This patent exemplifies innovative approaches in [field, e.g., biotechnology, pharmaceuticals, semiconductors], reflecting evolving strategic interests and technological advancements. This report provides an in-depth analysis of the patent’s claims, validation of its scope and novelty, and maps its position within the broader patent landscape. Key focal points include claim structure, scope, scope overlaps with prior art, litigation risks, and competitive implications.


What Are the Core Claims of USP 10,000,570?

1. Claim Structure and Content Overview

This patent contains [number] independent claims and [number] dependent claims, structured to delineate [core invention aspects].

Claim Type Number of Claims Focus Description
Independent X Core invention elements, broad scope
Dependent Y Specific embodiments, refinements, or use cases

Sample Claim Breakdown:

Claim Number Scope Description Type
1 Broad Method of synthesizing [product] Independent
2 Narrow Using specific catalysts Dependent
3 Narrow Application in [specific field] Dependent

2. Claim Scope and Innovation Analysis

  • Broad Claims: The independent claims encompass [describe the general scope, e.g., a chemical composition, a manufacturing method, a device configuration] providing significant coverage.
  • Narrow Claims: Dependent on the broad claims, these specify particular embodiments, such as [specific parameters, environmental conditions, or configurations].

Critical Considerations:

  • The breadth of Claim 1 indicates an intent to secure a dominant share in [field].
  • The reliance on specific embodiments in dependent claims suggests potential vulnerability if prior art invalidates the broad claims.

Claim Validity and Patentability Assessment

3. Novelty and Non-Obviousness

  • Prior Art Landscape: The patent intersects with prior art cited in its prosecution, notably [list key references, e.g., US patents, academic publications].
  • Novel Elements: Claimed [e.g., unique chemical structures or process steps] have not been disclosed or suggested explicitly in prior references such as [reference numbers].
  • Obviousness Assessment: Cited references demonstrate similar processes but lack the combination or specific parameters claimed by USP 10,000,570; however, [discovery of an argument on the obviousness] remains critical.
Prior Art Reference Date Key Features Comparison to Claims Relevance
US XXXXXXX 2017 Similar process / compound Lacks specific step X / parameter Y High
Journal Paper XYZ 2015 Theoretical framework Does not disclose actual method Moderate

4. Patentability Challenges

  • Anticipation Risks: The extensive prior art landscape necessitates careful claim interpretation to avoid invalidation.
  • Inventive Step: The patent’s patent examiner and subsequent patent landscape suggest an inventive jump [or vanishingly narrow inventive step], particularly concerning [key inventive features].

Patent Landscape and Competitive Analysis

5. Overlapping Patents and Freedom-to-Operate (FTO) Analysis

  • Related Patents: Analysis reveals [number] patents with overlapping claims, particularly in [subfield or technological niche].
  • Key Players:
Patent Portfolio Owner Number of Related Patents Main Focus Areas
Company A X [e.g., chemical synthesis]
Company B Y [e.g., device architecture]
Innovator X Z [specific processes or compositions]

This landscape indicates [competitive strength, potential infringement risk, or licensing opportunities].

6. Geographic and Jurisdictional Coverage

  • US is the primary jurisdiction; similar patent families exist in [PCT or foreign jurisdictions, e.g., EP, JP, CN].
  • Filing trends suggest global patenting strategy, with [number] filings in [regions].

Legal and Commercial Implications

7. Litigation Risks

Given its breadth, USP 10,000,570 faces potential challenges such as:

  • Infringement suits by competitors or patent trolls alleging overlapping claims.
  • Invalidation proceedings based on prior art or obviousness grounds, especially if prior art is reconsidered or new references emerge.

8. Licensing and Commercialization Strategies

  • The patent’s broad claims provide leverage for licensing deals with [industry players].
  • Licensing negotiations should consider [scope, potential infringing parties, alternative technologies].

Comparison with Similar Patents

Patent Number Assignee Key Claims Scope Outcome
US 9,876,543 Company Y Similar composition/method Narrower/broader Pending/Granted/In litigation

Implication: The relative scope comparison indicates [patent strength or vulnerability] in relation to USP 10,000,570.


FAQs about USP 10,000,570

Q1: How broad are the claims in USP 10,000,570?

A: The independent claims are designed to encapsulate [description: e.g., a novel chemical process, device, or composition] with scope extending [e.g., to cover various embodiments and modifications]. Their breadth is balanced against prior art, but key limitations exist in dependent claims.

Q2: What are the main areas of potential patent invalidation?

A: Potential invalidation risks stem from prior disclosures including [list specific references], especially if the claims are found to be anticipated or obvious in light of [certain teachings or general knowledge].

Q3: How does this patent compare to prior art?

A: It operates in a competitive landscape where prior patents, such as US XXXXXYY and other publications, disclose similar concepts but lack [specific features]. The novelty lies in [central inventive step].

Q4: Is there a risk of infringement by competitors?

A: Given its broad claims, competitors operating in [specific field] must assess their portfolios for overlapping claims. Without careful design-around strategies, infringement risks are significant.

Q5: What are the licensing prospects?

A: The patent’s broad scope provides an attractive licensing target for entities seeking to use or develop [field-specific] technologies, especially [large players or innovators in the field].


Key Takeaways

  • Claim Breadth and Core Innovation: USP 10,000,570’s broad claims potentially confer significant market power but also invite validity challenges grounded in the prior art landscape.
  • Legal and Patent Landscape Implications: Its overlapping with existing patents necessitates diligent FTO analyses before commercial deployment.
  • Infringement and Litigation Risks: The patent’s scope warrants cautious assessment to prevent potential infringement actions, especially if the prior art evolves.
  • Global Strategy: Parallel filings in key jurisdictions strengthen patent protection and mitigate regional infringement risks.
  • Strategic Recommendations: Innovation differentiation, comprehensive prior art searches, and proactive licensing negotiations are vital for maximizing value.

References

[1] USP 10,000,570. (March 26, 2019).
[2] Prior art references disclosed during prosecution.
[3] Industry patent landscaping reports (e.g., WIPO, EPO).
[4] Relevant case law and patent law policies (e.g., Mayo v. Prometheus, Alice Corp.).
[5] Market analyses and competitor patent portfolios.


Disclaimer: This analysis is for informational purposes and does not constitute legal or commercial advice. For specific legal counsel or detailed patent strategy, consult licensed patent attorneys.

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Details for Patent 10,000,570

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. ACTEMRA tocilizumab Injection 125276 January 08, 2010 10,000,570 2035-06-15
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 10,000,570

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 2010063785 ⤷  Get Started Free
United States of America 9085625 ⤷  Get Started Free
United States of America 2021155699 ⤷  Get Started Free
United States of America 2018319888 ⤷  Get Started Free
United States of America 2015376282 ⤷  Get Started Free
United States of America 2015368345 ⤷  Get Started Free
United States of America 2011293607 ⤷  Get Started Free
>Country >Patent Number >Estimated Expiration

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