Patent: 10,000,553
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Summary for Patent: 10,000,553
Title: | CD40L-specific TN3-derived scaffolds and methods of use thereof |
Abstract: | The present invention provides Tenascin-3 FnIII domain-based scaffolds that specifically bind to CD40L. The invention further provides engineered variants with increased affinity for the target. The present invention is also related to engineered scaffolds as prophylactic, diagnostic, or therapeutic agents, in particular for therapeutic uses against SLE and other autoimmune diseases and conditions. |
Inventor(s): | Coyle; Anthony (Boston, MA), Baca; Manuel (Gaithersburg, MD), Thisted; Thomas (Gaithersburg, MD), Drabic; Stacey (Gaithersburg, MD), Grinberg; Luba (Gaithersburg, MD), Novarra; Shabazz (Gaithersburg, MD), Oganesyan; Vaheh (Gaithersburg, MD), Herbst; Ronald (Gaithersburg, MD), Spencer; David Kenneth (Gaithersburg, MD) |
Assignee: | Viela Bio, Inc. (Gaithersburg, MD) |
Application Number: | 14/347,016 |
Patent Claims: | see list of patent claims |
Details for Patent 10,000,553
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Grifols Therapeutics Llc | ALBUKED, PLASBUMIN-20, PLASBUMIN-25, PLASBUMIN-5 | albumin (human) | For Injection | 101138 | 10/21/1942 | ⤷ Try a Trial | 2031-10-11 |
Baxalta Us Inc. | BUMINATE, FLEXBUMIN | albumin (human) | Injection | 101452 | 03/03/1954 | ⤷ Try a Trial | 2031-10-11 |
Csl Behring Ag | ALBURX | albumin (human) | Injection | 102366 | 07/23/1976 | ⤷ Try a Trial | 2031-10-11 |
Grifols Biologicals Llc | ALBUTEIN | albumin (human) | Injection | 102478 | 08/15/1978 | ⤷ Try a Trial | 2031-10-11 |
Instituto Grifols, S.a. | HUMAN ALBUMIN GRIFOLS | albumin (human) | Injection | 103352 | 02/17/1995 | ⤷ Try a Trial | 2031-10-11 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |