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Last Updated: September 24, 2020

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Patent: 10,000,553

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Summary for Patent: 10,000,553
Title:CD40L-specific TN3-derived scaffolds and methods of use thereof
Abstract: The present invention provides Tenascin-3 FnIII domain-based scaffolds that specifically bind to CD40L. The invention further provides engineered variants with increased affinity for the target. The present invention is also related to engineered scaffolds as prophylactic, diagnostic, or therapeutic agents, in particular for therapeutic uses against SLE and other autoimmune diseases and conditions.
Inventor(s): Coyle; Anthony (Boston, MA), Baca; Manuel (Gaithersburg, MD), Thisted; Thomas (Gaithersburg, MD), Drabic; Stacey (Gaithersburg, MD), Grinberg; Luba (Gaithersburg, MD), Novarra; Shabazz (Gaithersburg, MD), Oganesyan; Vaheh (Gaithersburg, MD), Herbst; Ronald (Gaithersburg, MD), Spencer; David Kenneth (Gaithersburg, MD)
Assignee: Viela Bio, Inc. (Gaithersburg, MD)
Application Number:14/347,016
Patent Claims:see list of patent claims

Details for Patent 10,000,553

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial Viela Bio, Inc. (Gaithersburg, MD) 2031-10-11 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial Viela Bio, Inc. (Gaithersburg, MD) 2031-10-11 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial Viela Bio, Inc. (Gaithersburg, MD) 2031-10-11 search
Grifols Usa, Llc ALBUTEIN albumin (human) INJECTION, SOLUTION 102478 1 2019-12-15   Start Trial Viela Bio, Inc. (Gaithersburg, MD) 2031-10-11 search
Grifols Usa, Llc HUMAN ALBUMIN GRIFOLS albumin (human) SOLUTION 103352 1 2003-06-11   Start Trial Viela Bio, Inc. (Gaithersburg, MD) 2031-10-11 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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