Last Updated: June 25, 2026

Biologic Patents Expiring in 2044

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Biologic Patents With Estimated Expirations in 2044

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Akorn, Inc.	HYDASE	hyaluronidase	Injection	021716	October 25, 2005	⤷ Start Trial	2044-03-08
Akorn, Inc.	HYDASE	hyaluronidase	Injection	021716	October 25, 2005	⤷ Start Trial	2044-07-19
Omrix Biopharmaceuticals Ltd	EVITHROM	thrombin, topical (human)	Solution	125247	August 27, 2007	⤷ Start Trial	2044-01-22
Omrix Biopharmaceuticals Ltd	EVITHROM	thrombin, topical (human)	For Injection	125247	September 17, 2009	⤷ Start Trial	2044-01-22
Horizon Therapeutics Ireland Dac	KRYSTEXXA	pegloticase	Injection	125293	September 14, 2010	⤷ Start Trial	2044-04-09
Regeneron Pharmaceuticals, Inc.	EYLEA	aflibercept	Injection	125387	November 18, 2011	⤷ Start Trial	2044-10-23
Regeneron Pharmaceuticals, Inc.	EYLEA	aflibercept	Injection	125387	August 16, 2018	⤷ Start Trial	2044-10-23
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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