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Last Updated: March 26, 2026

Claims for Patent: 9,982,033


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Summary for Patent: 9,982,033
Title:Factor VIII polypeptide titers in cell cultures
Abstract:The invention relates to a method for the production of a Factor VIII polypeptide, the method comprising the steps of a) culturing a mammalian cell expressing a Factor VIII polypeptide under conditions for expression of said Factor VIII polypeptide, said culturing conditions involving a cell culture medium comprising a C2-domain ligand, and b) isolating the expressed Factor VIII polypeptide from the mammalian cell by suitable means.
Inventor(s):Johnsen Laust Bruun, Hilden Ida, Bolt Gert, Steenstrup Thomas Dock
Assignee:Novo Nordisk A/S
Application Number:US12597118
Patent Claims:

Details for Patent 9,982,033

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Wyeth Pharmaceuticals Llc REFACTO antihemophilic factor (recombinant) For Injection 103779 June 27, 2001 ⤷  Start Trial 2028-04-30
Wyeth Pharmaceuticals Llc REFACTO antihemophilic factor (recombinant) For Injection 103779 July 06, 2001 ⤷  Start Trial 2028-04-30
Novo Nordisk Inc. NOVOEIGHT antihemophilic factor (recombinant) For Injection 125466 October 15, 2013 ⤷  Start Trial 2028-04-30
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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