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Last Updated: April 26, 2024

Claims for Patent: 9,765,353

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Summary for Patent: 9,765,353

Title:	Plant having suppressed expression of glycoalkaloid biosynthetic enzyme gene or altered activity of the enzyme
Abstract:	Provided are the DNA of a glycoalkaloid biosynthetic enzyme of solanaceous plants (Solanaceae) such as potato, solanaceous plants producing no glycoalkaloids, and a method of producing a cultivar with a reduced risk of accumulating glycoalkaloids, which involves crossing plants in which the expression of an oxidase gene involved in glycoalkaloid biosynthesis is suppressed or the activity of the enzyme is lowered, as mother plants, and screening progeny resulting from the crossing.
Inventor(s):	Umemoto; Naoyuki (Nakano-ku, JP)
Assignee:	KIRIN HOLDINGS KABUSHIKI KAISHA (Nakano-ku, Tokyo, JP)
Application Number:	14/382,913
Patent Claims:	1. A method of producing a potato plant containing no glycoalkaloids, which comprises: (i) obtaining progeny plants by crossing a plant as a mother plant, in which the expression of an oxidase gene involved in glycoalkaloid biosynthesis is suppressed such that glycoalkaloids are not produced; (ii) screening for the progeny plants, in which the expression of an oxidase gene involved in glycoalkaloid biosynthesis is suppressed such that glycoalkaloids are not produced; and (iii) selecting the progeny plant containing no glycoalkaloids, wherein the mother plant is a plant containing an insertion sequence that comprises the sequences set forth in SEQ ID NO: 23 and SEQ ID NO: 24 in the 4.sup.th intron of the oxidase gene, an insertion sequence that comprises the sequence set forth in SEQ ID NO: 25 and the sequence set forth in SEQ ID NO: 26, or an insertion sequence consisting of a partial sequence thereof.

Details for Patent 9,765,353

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2032-03-07
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2032-03-07
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2032-03-07
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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