Claims for Patent: 9,561,080

Summary for Patent: 9,561,080

Title:	Internal body cavity therapeutic applicator arrangements and methods for using the same
Abstract:	An apparatus for providing at least one treatment to at least one tissue having a first structural arrangement configured to expand a first portion at a distal end of the apparatus, a second structural arrangement configured to expand a second portion at the distal end and at least one lumen associated with at least one of the first structural arrangement and/or the second structural arrangement. The first structural arrangement and/or the second structural arrangement can be configured to position the at least one lumen at a particular position with respect to the tissue. A tip is configured to aid in the insertion of the apparatus into the tissue(s).
Inventor(s):	Lamoureux; Gary A. (Woodbury, CT), Cohen; Gil\'Ad N. (Tenafly, NJ), Goodman; Karyn (New York, NY)
Assignee:	Memorial Sloan-Kettering Cancer Center (New York, NY) GC Medtech LLC (Hialeah, FL)
Application Number:	14/348,781
Patent Claims:	1. An apparatus for providing at least one treatment to at least one tissue, comprising: a first structural arrangement configured to expand a first portion at a distal end of the apparatus; a second structural arrangement configured to expand a second portion at the distal end; and at least one lumen extending from a proximal end of the apparatus to the distal end, and having an opening at the proximal end, wherein the at least one lumen is located between and separate from the first structural arrangement and the second structural arrangement; wherein the first structural arrangement is configured to position the at least one lumen at a particular position with respect to the at least one tissue based on an expansion of the first portion, and wherein the second structural arrangement is configured to position the at least one lumen at the particular position with respect to the at least one tissue based on an expansion of the second portion, and wherein at least one of the first structural arrangement or the second structural arrangement is a baffle filled with at least one of sterile water or air. 2. The apparatus of claim 1 further comprising a tip portion provided at the distal end and configured to facilitate an insertion of the apparatus into the at least one tissue. 3. The apparatus of claim 1, wherein the second structural arrangement is configured to expand the at least one tissue. 4. The apparatus of claim 1, wherein the at least one lumen is configured and structured to provide a radiation source through the opening. 5. The apparatus of claim 1, wherein the at least one lumen comprises at least eight lumens equally spaced apart circumferentially around the distal end. 6. The apparatus of claim 5, wherein one of the lumens is visibly labeled or marked to provide a reference point for all of the lumens. 7. The apparatus of claim 1, wherein the at least one lumen is configured to receive a treatment option. 8. The apparatus of claim 7, wherein the treatment option is at least one of a radiation source or a pharmacological agent. 9. The apparatus of claim 1, further comprising a second lumen located substantially in a center of the apparatus. 10. The apparatus of claim 1, wherein the apparatus is configured to be guided into a tubular structure using at least one of at least an endoscope, a cable or a wire. 11. The apparatus of claim 1, further comprising markers at least one of spaced equally apart at the proximal end of the apparatus to determine a distance at which the apparatus is inserted into the at least one tissue or spaced along the distal end which are provided to be detected by an imaging arrangement to aid in insertion of the apparatus. 12. The apparatus of claim 1, wherein the first structural arrangement and the second structural arrangement are baffles filled with at least one of the sterile water or the air, and further comprising at least one of a single baffle source for inflating the first structural arrangement and the second structural arrangement or two baffle sources, one of the baffle sources provided for inflating the first structural arrangement and the other of the baffle sources provided for inflating the second structural arrangement. 13. The apparatus of claim 1, further comprising at least one of a single source for inflating the first structural arrangement and the second structural arrangement or two sources, one of the sources provided for inflating the first structural arrangement and the other of the sources provided for inflating the second structural arrangement. 14. The apparatus of claim 1, wherein the apparatus includes at least one of an anorectal applicator, an esophageal applicator, a sigmoid applicator or a colon applicator. 15. An apparatus for providing at least one treatment to at least one tissue, comprising: a first baffle arrangement configured to inflate a first portion provided at a distal end of the apparatus so as to expand the at least one tissue; a second baffle arrangement configured to inflate a second portion provided at the distal end; a plurality of source lumens extending from a proximal end of the apparatus to the distal end, each of the source lumens having an opening at the proximal end, wherein the plurality of source lumens are located between and separate from the first baffle arrangement and the second baffle arrangement; and a tip portion located at the distal end, and configured to aid in the insertion of the apparatus into a tubular structure; wherein the first baffle arrangement is configured to position at least one of the source lumens at a surface of the at least one tissue based on an expansion of the first portion, and wherein the second baffle arrangement is configured to position at least one of the source lumens at the surface of the at least one tissue based on an expansion of the second portion. 16. The apparatus of claim 15, wherein the plurality of lumens comprises at least eight lumens equally spaced circumferentially apart around the distal end with one lumen labeled or marked to provide a reference point for all of the lumens. 17. The apparatus of claim 15, wherein the plurality of lumens are configured to receive a treatment option through the opening. 18. The apparatus of claim 17, wherein the treatment option is at least one of at least a radiation source or a pharmacological agent. 19. The apparatus of claim 15 further comprising a second lumen, in addition to the source lumens, located substantially in a center of the apparatus. 20. The apparatus of claim 15, wherein the apparatus is configured to be guided into the at least one tissue using at least one of an endoscope, a cable or a wire. 21. The apparatus of claim 15, further comprising markers at least one of spaced equally apart at the proximal end of the apparatus to determine a distance the apparatus is inserted into the at least one tissue or spaced along the distal end which are provided to be detected by an imaging arrangement to aid in insertion of the apparatus. 22. The apparatus of claim 15, wherein the first baffle arrangement and the second baffle arrangement are filled with at least one of sterile water or air. 23. The apparatus of claim 15, further comprising a single baffle source for inflating the first baffle arrangement and the second baffle arrangement or two baffle sources, one of the baffle sources provided for inflating the first baffle arrangement and another of the baffle sources provided for inflating the second baffle arrangement. 24. The apparatus of claim 15, wherein the apparatus includes at least one of an anorectal applicator, an esophageal applicator, a sigmoid applicator, or a colon applicator. 25. A method for treating a patient using an apparatus configured to provide at least one radiation treatment to at least one tissue of the patient, comprising: inserting the apparatus into the at least one tissue; expanding a first portion at a distal end of the apparatus using a first baffle arrangement that is filled with at least one of sterile water or air, expanding a second portion at the distal end using a second baffle arrangement that is filled with at least one of the sterile water or the air; positioning at least one lumen at a particular position with respect to the tissue, wherein the at least one lumen extends from a proximal end of the apparatus to the distal end, and has an opening at the proximal end, and wherein the at least one lumen is located between and separate from the first structural arrangement and the second structural arrangement; inserting at least one radiation source into the at least one lumen; applying, using the at least one radiation source, the at least one radiation treatment directly to an internal portion of the at least one tissue which includes a disorder; contracting at least one of the first arrangement or the second arrangement; and removing the at least one radiation source and the apparatus from the at least one tissue. 26. The method of claim 25 further comprising using an imaging device to aid in an insertion of the apparatus. 27. The method of claim 26, further comprising providing markers at least one of spaced along the distal end capable of being detected by the imaging device to aid in the insertion of the apparatus or spaced equally apart at a proximal end of the apparatus to determine a distance of an insertion of the apparatus into the at least one tissue. 28. The method of claim 27, further comprising marking a distance marker on the apparatus, and reinserting the apparatus only to a position of the marked distance marker. 29. An apparatus for providing at least one treatment to at least one tissue, comprising: a first baffle filled with at least one of sterile water or air, and configured to expand a first portion at a distal end of the apparatus; a second baffle filled with the at least one of the sterile water or the air, and configured to expand a second portion at the distal end; and at least one lumen extending from a proximal end of the apparatus to the distal end, and having an opening at the proximal end, wherein the at least one lumen is located between and separate from the first baffle and the second baffle; wherein the first baffle is configured to position the at least one lumen at a particular position with respect to the at least one tissue based on an expansion of the first portion, and wherein the second baffle is configured to position the at least one lumen at the particular position with respect to the at least one tissue based on an expansion of the second portion.

Details for Patent 9,561,080

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	ZOSTAVAX	zoster vaccine live	For Injection	125123	05/25/2006		2031-09-30