Last Updated: July 21, 2026

Claims for Patent: 8,871,439

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Summary for Patent: 8,871,439

Title:	Serum-free stable transfection and production of recombinant human proteins in human cell lines
Abstract:	The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free conditions with a specific vector carrying the gene coding for the protein of interest. Furthermore the invention relates to a production cell line obtained by said method, a production method for said protein of interest utilizing said production cell line, and the specific vector carrying the gene of interest itself.
Inventor(s):	Carola Schroeder, Haiyan Ding, Cathleen Wegmann
Assignee:	Octapharma AG
Application Number:	US11/993,604

Details for Patent 8,871,439

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Octapharma Pharmazeutika Produktionsges.m.b.h.	NUWIQ	antihemophilic factor (recombinant)	For Injection	125555	September 04, 2015	8,871,439	2026-06-29
Octapharma Pharmazeutika Produktionsges.m.b.h.	NUWIQ	antihemophilic factor (recombinant)	For Injection	125555	July 07, 2017	8,871,439	2026-06-29
Octapharma Pharmazeutika Produktionsges.m.b.h.	NUWIQ	antihemophilic factor (recombinant)	For Injection	125555	December 07, 2021	8,871,439	2026-06-29
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 8,871,439

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Country	Patent Number	Estimated Expiration
South Africa	200711013	⤷ Start Trial
World Intellectual Property Organization (WIPO)	2007003582	⤷ Start Trial
United States of America	2010184141	⤷ Start Trial
United States of America	2015044720	⤷ Start Trial
United States of America	2016177362	⤷ Start Trial
United States of America	2017152523	⤷ Start Trial
United States of America	9273325	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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