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Last Updated: December 29, 2025

Claims for Patent: 8,790,648

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Summary for Patent: 8,790,648

Title:	Methods of treating psoriasis using IL-17 receptor A antibodies
Abstract:	The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
Inventor(s):	Tocker Joel, Peschon Jacques J., Fitzpatrick David, Smothers James F., Mehlin Christopher, Lim Ai Ching
Assignee:	Amgen Inc.
Application Number:	US13472074
Patent Claims:

Details for Patent 8,790,648

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Valeant Pharmaceuticals Luxembourg S.à.r.l.	SILIQ	brodalumab	Injection	761032	February 15, 2017	⤷ Get Started Free	2032-05-15
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 8,790,648

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Country	Patent Number	Estimated Expiration
South Africa	200902018	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2008054603	⤷ Get Started Free
United States of America	9096673	⤷ Get Started Free
United States of America	9073999	⤷ Get Started Free
United States of America	8545842	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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