Claims for Patent: 8,613,261

Summary for Patent: 8,613,261

Title:	Method of making a degradable animal chew toy
Abstract:	A chew for a domestic animal comprises one or more sheets of a chewable bovine rawhide formed into a shape suitable for chewing by a domestic animal, wherein the one or more sheets has a mass loss of at least 45% as measured by the Degradability Standard Test Protocol. The bovine rawhide is made with a process that includes treatment with an enzyme. A process of making a pet chew from a split bovine hide comprises treating the split bovine hide with an enzyme solution.
Inventor(s):	Mendal; Isaac (Deerfield Beach, FL), Urbina; Augusto (Bogota, CO)
Assignee:	Salix Animal Health, LLC (Deerfield Beach, FL)
Application Number:	13/296,484
Patent Claims:	1. A process of making a pet chew from a clean, split bovine hide that has been washed and de-haired, comprising: treating the split bovine hide with a deliming solution to provide a delimed split bovine hide; treating the delimed split bovine hide with an enzyme solution for a time and temperature to improve the degradability of the bovine hide without significantly affecting the chewable quality of the hide to provide an enzyme treated split bovine hide; washing the enzyme treated split bovine hide to remove the enzyme solution; and forming the thus treated split bovine hide into a shaped pet chew, wherein the pet chew has a mass loss of at least 45% as measured by the Degradability Standard Test Protocol. 2. The process of claim 1 and further comprising bleaching the washed split bovine hide with a bleaching solution. 3. The process of claim 1 wherein the enzyme treating act is carried out for 30-60 minutes and at a temperature in the range of 20-45.degree. C. 4. The process of claim 3 wherein the enzyme solution has a pH in the range of 8.0-11.0. 5. The process of claim 1 wherein the enzyme solution comprises a mixture of enzymes. 6. The process of claim 1 wherein the enzyme in the enzyme solution is selected from the group of oxidoreductase, transferase, hydrolase, lyase and isomerase enzyme classes and combinations thereof. 7. The process of claim 6 wherein the oxidoreductase enzyme is at least one of a peroxidase, catalase, glucose oxidase, laccase and combinations thereof. 8. The process of claim 6 wherein the transferase enzyme is at least one of a fructosyl transferase, glucosyl transferase and combinations thereof. 9. The process of claim 6 wherein the hydrolase enzyme is at least one of a lipase, protease, glycosylase and combinations thereof. 10. The process of claim 9 wherein the hydrolase enzyme is at least one of trypsin, chymotrypsin, pepsin and combinations thereof. 11. The process of claim 9 wherein the hydrolase enzyme is at least one of a collagenase, a gelatinase and combinations thereof. 12. The process of claim 6 wherein the hydrolase enzyme is at least one of a serine peptidase, cysteine peptidase, threonine peptidase, glutamic peptidase, aspartic peptidase, metallopeptidase and combinations thereof. 13. The process of claim 6 wherein the lyase enzyme is at least one of a pectin lyase, pectate lyase, acetolactate decarboxylase and combinations thereof. 14. The process of claim 6 wherein the isomerase enzyme is at least one of a glucose isomerase, xylose isomerase and combinations thereof. 15. The process of claim 1 wherein the wherein the pet chew has a mass loss of at least 50% as measured by the Degradability Standard Test Protocol. 16. The process of claim 1 wherein the pet chew has a mass loss of at least 60% as measured by the Degradability Standard Test Protocol.

Details for Patent 8,613,261

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965		2030-11-22