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Last Updated: April 26, 2024

Claims for Patent: 8,552,153

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Summary for Patent: 8,552,153

Title:	Coral-derived collagen and methods of farming same
Abstract:	An isolated collagen fiber is disclosed, wherein a length of the fiber prior to stretching by about 15%, is identical to a length of the fiber following said stretching by about 15%. The fiber comprises a Nuclear Magnetic Resonance (NMR) spectroscopic profile as shown in FIG. 1. Uses thereof and method of isolating are also disclosed.
Inventor(s):	Benayahu; Yehuda (Herzlia, IL), Benayahu; Dafna (Herzlia, IL), Kashman; Yoel (Tel-Aviv, IL), Rudi; Amira (Ramat-HaSharon, IL), Lanir; Yoram (Haifa, IL), Sella; Ido (Tel-Aviv, IL), Raz; Einat (Mitzpe Aviv-Doar-Na Misgav, IL)
Assignee:	Ramot at Tel-Aviv University Ltd. (Tel-Aviv, IL)
Application Number:	12/934,704
Patent Claims:	1. An isolated collagen fiber being extracted from a Sarcophyton sp soft coral. 2. The isolated collagen fiber of claim 1, having a stiffness about 30-50% lower than that of mammalian collagen. 3. The isolated collagen fiber of claim 1, having a tensile strength about half of mammalian collagen. 4. The isolated collagen fiber of claim 1, being resistant to degradation by trypsin and collagenase. 5. The isolated collagen fiber of claim 1, wherein a length of said fiber prior to stretching by about 15%, is identical to a length of said fiber following said stretching by about 15%. 6. A scaffold comprising the isolated collagen fiber of claim 1. 7. The scaffold of claim 6, further comprising cells. 8. A cell culture comprising mammalian cells seeded on the isolated collagen fiber of claim 1. 9. A composite comprising, as a first component, the isolated collagen fiber of claim 1 and a second component selected from the group consisting of a mineral, a polysaccharide and a polypeptide. 10. A pharmaceutical composition comprising the isolated collagen fiber of claim 1. 11. A cosmetic composition comprising the isolated collagen fiber of claim 1. 12. A method of regenerating tissue, the method comprising providing to a subject in need-thereof the scaffold of claim 6, thereby regenerating tissue.

Details for Patent 8,552,153

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965	⤷ Try a Trial	2028-03-27
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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