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Last Updated: April 26, 2024

Claims for Patent: 8,513,193


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Summary for Patent: 8,513,193
Title:Protecting and repairing cartilage and musculoskeletal soft tissues
Abstract: Provided herein are compositions and methods related to promoting protection or repair of articular cartilage and/or musculoskeletal soft tissue by contacting the cartilage, tissues or cellular components thereof with a parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) receptor agonist or releasing factor.
Inventor(s): Rosier; Randy N. (Rochester, NY), Zuscik; Michael J. (North Chili, NY), Sampson; Erik (Rochester, NY), Bukata; Susan V. (Pittsford, NY), Puzas; J. Edward (Pittsford, NY), Awad; Hani (Rochester, NY)
Assignee: University of Rochester (Rochester, NY)
Application Number:13/124,002
Patent Claims:1. A method of promoting repair of articular cartilage in a subject comprising a. selecting a human subject with injured articular cartilage; and b. administering intermittently to the subject a parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) receptor agonist, wherein the cartilage is injured by trauma.

2. The method of claim 1, wherein the PTH/PTHrP receptor agonist is a peptide agonist.

3. The method of claim 2, wherein the peptide agonist is teriparatide.

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