Claims for Patent: 8,353,963

Summary for Patent: 8,353,963

Title:	Expandable spacer and method for use thereof
Abstract:	An expandable implant is disclosed having an adjustable height for insertion between two adjacent bony structures or joint surfaces, for example between two adjacent spinal vertebrae. The implant includes at least one gear associated with at least one threaded shaft. Rotation of the gear engages the threaded shaft to expand the implant. The implant can be inserted in a collapsed configuration and expanded in situ. The invention also provides methods for using the implant to facilitate arthrodesis or fusion of adjacent joint surfaces or spinal vertebrae.
Inventor(s):	Glerum; Chad (Pennsburg, PA)
Assignee:	Globus Medical (Audubon, PA)
Application Number:	12/615,806
Patent Claims:	1. An expandable implant for insertion in a space between adjacent bony structures, comprising: a first threaded shaft and a second threaded shaft; a base plate coupled to the first threaded shaft and the second threaded shaft; and a first gear and a second gear operably coupled with said first threaded shaft and said second threaded shaft, respectively, and operably coupled with said base plate, said first gear and said second gear having respective interior surfaces including threads matably engaged with respective said first threaded shaft and said second threaded shaft, whereby rotation of said first gear and said second gear initiates displacement of said first threaded shaft and said second threaded shaft within said base plate, whereby said first threaded shaft and said second threaded shaft are extendable in a direction away from said base plate; wherein the first threaded shaft and the second threaded shaft are coupled to a top plate; wherein the first gear and the second gear are positioned with an axis parallel to the interior surface extending substantially perpendicular to a longitudinal axis of the base plate and adjacent to one another; wherein the first gear and the second gear are operably coupled to one another whereby rotation of the first gear in a first direction initiates rotation of the second gear in the first direction. 2. The expandable implant according to claim 1, wherein the expandable implant has a first, collapsed height prior to extension of said first threaded shaft and said second threaded shaft and a second, expanded height after extension of said first threaded shaft and said second threaded shaft. 3. The expandable implant according to claim 2, wherein the second, expanded height is adjustable. 4. The expandable implant according to claim 1, wherein the implant is operable to distract the adjacent bony structures. 5. The expandable implant according to claim 1, wherein the space is the intervertebral space between two adjacent spinal vertebrae. 6. The expandable implant according to claim 1, wherein said first threaded shaft and said second threaded shaft each have a hollow interior. 7. The expandable implant according to claim 6, wherein a top end of said first threaded shaft and a top end of said second threaded shaft each include an opening, the opening operable for insertion of material into said hollow interiors. 8. The expandable implant according to claim 7, wherein the material is a bone graft material selected from a group consisting of autograft material, allograft material, xenograft material, artificial mixtures, synthetic mixtures, demineralized bone matrix, hydroxyapatite mixtures, and combinations thereof. 9. The expandable implant according to claim 8, wherein the bone graft material further includes an effective amount of a growth factor or differentiation factor. 10. The expandable implant according to claim 9, wherein the growth factor or differentiation factor is selected from a group consisting of bone morphogenic protein (BMP), transforming growth factor 131 (TGF131), insulin-like growth factor 1 (IGF-1), platelet-derived growth factor (PDGF), activin, parathyroid hormone, fibroblast growth factor (FGF), LIM mineralization protein (LMP), and combinations thereof. 11. The expandable implant according to claim 1, wherein the implant is formed from a material selected from a group consisting of titanium, titanium alloys, stainless steel, chrome cobalt, nickel, ceramics, plastics, shape-memory alloys, bioactive glass, composites, bone, bone substitutes, and combinations thereof. 12. An expandable implant for insertion in a space between adjacent bony structures comprising: a first threaded shaft; a second threaded shaft; a bottom plate having an exterior surface and an interior surface, the interior surface including a base receiving the first threaded shaft and the second threaded shaft; and a pair of coupled actuation gears comprising a first gear of the pair having a first interior gear surface operably coupled to the first threaded shaft, further comprising a second gear of the pair having a second interior gear surface operably coupled to the second threaded shaft; whereby rotation of the first gear in a first direction initiates rotation of the second gear in a second direction, opposite the first direction, initiating rotation of the first threaded shaft and then the second threaded shaft such that the shafts extend to engage adjacent bony structures; wherein the first gear and the second gear are directly coupled to each other and are positioned with a longitudinal axis of the first interior gear surface and a longitudinal axis of the second interior gear surface extending perpendicular to a longitudinal axis of the base plate. 13. The expandable implant according to claim 12, wherein the first threaded shaft and the second threaded shaft are in a substantially parallel configuration. 14. The expandable implant according to claim 12, wherein the base holds the first threaded shaft and the second threaded shaft in an angled configuration.

Details for Patent 8,353,963

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Nps Pharmaceuticals, Inc.	NATPARA	parathyroid hormone	For Injection	125511	01/23/2015		2039-03-29