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Last Updated: December 28, 2025

Claims for Patent: 8,329,871

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Summary for Patent: 8,329,871

Title:	Process of purifying coagulation factor VIII
Abstract:	A process of purifying or enriching coagulation FVIII employing chromatography comprising the steps of providing a fraction containing FVIII in an aqueous solution having a high ionic strength; contacting the fraction containing FVIII with a multimodal resin; optionally washing the multimodal resin having FVIII adsorbed with an aqueous washing buffer; eluting FVIII containing fractions by an aqueous elution buffer comprising at least one amino acid which is positively charged at pH 6 to 8; and optionally collecting FVIII containing fractions in purified or enriched form.
Inventor(s):	Carin Borgvall, Ulrika Ericsson, Gustav Gilljam, Mats Jernberg, Stefan Winge
Assignee:	Octapharma AG
Application Number:	US12/737,230

Details for Patent 8,329,871

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Octapharma Pharmazeutika Produktionsges.m.b.h.	NUWIQ	antihemophilic factor (recombinant)	For Injection	125555	September 04, 2015	8,329,871	2029-06-24
Octapharma Pharmazeutika Produktionsges.m.b.h.	NUWIQ	antihemophilic factor (recombinant)	For Injection	125555	July 07, 2017	8,329,871	2029-06-24
Octapharma Pharmazeutika Produktionsges.m.b.h.	NUWIQ	antihemophilic factor (recombinant)	For Injection	125555	December 07, 2021	8,329,871	2029-06-24
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 8,329,871

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Country	Patent Number	Estimated Expiration
South Africa	201009162	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2009156430	⤷ Get Started Free
United States of America	2011160435	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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