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Last Updated: May 1, 2024

Claims for Patent: 8,329,231

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Summary for Patent: 8,329,231

Title:	Method of preventing photo-aging with ashwagandha and Indian gooseberry
Abstract:	A method of preventing photo-aging and its related causes includes administering a therapeutic composition comprising extracts of the plant species ashwagandha (Withania somnifera) and Indian gooseberry (Phyllanthus emblica). A composition of ashwagandha and Indian gooseberry may: (1) lower cortisol and increase DHEA, (2) prevent free radical-induced photoaging, (3) inhibit collagenase activity in vitro, (4) inhibit hyaluronidase activity in vitro, (5) display superior cascading antioxidant activity, (6) reduce C-reactive protein, and (7) enhance mood.
Inventor(s):	McNeary; Peter (Brattleboro, VT)
Assignee:	Nutragenesis, LLC (Brattleboro, VT)
Application Number:	13/532,380
Patent Claims:	1. A method of reducing photoaging comprising administering to a human a therapeutic composition for internal consumption consisting essentially of a synergistically effective combination of extracts of Phyllanthus emblica and Withania somnifera wherein said Phyllanthus emblica and said Withania somnifera are present in the composition in a weight ratio of about 1:7 Phyllanthus emblica to Withania somnifera to a weight ratio of about 7:1 Phyllanthus emblica to Withania somnifera. 2. The method according to claim 1, wherein said administering limits free radical creation. 3. The method according to claim 1, wherein said Phyllanthus emblica and said Withania somnifera are present in the composition in a weight ratio of about 6:2 Phyllanthus emblica to Withania somnifera to a weight ratio of about 2:6 Phyllanthus emblica to Withania somnifera. 4. The method according to claim 1, wherein the Phyllanthus emblica and Withania somnifera are present in the composition in a weight ratio of about 6:2 Phyllanthus emblica to Withania somnifera to a weight ratio of about 3:5 Phyllanthus emblica to Withania somnifera. 5. The method according to claim 1, wherein the Phyllanthus emblica and Withania somnifera are present in the composition in a weight ratio of about 6:2 Phyllanthus emblica to Withania somnifera to a weight ratio of about 2:2 Phyllanthus emblica to Withania somnifera. 6. The method according to claim 1, wherein the Phyllanthus emblica and Withania somnifera are present in the composition in a weight ratio of about 5:3. 7. The method according to claim 1, wherein the composition comprises about 60 wt. % Withania somnifera to about 65 wt. % Withania somnifera and about 35 wt. % Phyllanthus emblica to about 40 wt. % Phyllanthus emblica. 8. The method according to claim 1, wherein the administering synergistically inhibits collagenases. 9. The method according to claim 1, wherein the administering synergistically inhibits hyaluronidase activity. 10. The method according to claim 1, wherein the synergistic combination is included in a beverage, nutritional product, or food product. 11. A method according to claim 1, wherein said administration synergistically chelates iron ions. 12. A method of reducing photoaging by limiting free radical creation in a human comprising: providing an extract of Phyllanthus emblica; providing an extract of Withania somnifera; combining the extract of Phyllanthus emblica and the extract of Withania somnifera in a weight ratio of about 1:7 Phyllanthus emblica to Withania somnifera to a weight ratio of about 7:1 Phyllanthus emblica to Withania somnifera so as to create a synergistically effective combination of the extracts; and adding the combination of extracts to a beverage, nutritional product, or food product for administering the resultant beverage, nutritional product or food product to a human in need thereof. 13. The method according to claim 12, wherein said Phyllanthus emblica and said Withania somnifera are present in the composition in a weight ratio of about 6:2 Phyllanthus emblica to Withania somnifera to a weight ratio of about 2:6 Phyllanthus emblica to Withania somnifera. 14. The method according to claim 12, wherein the Phyllanthus emblica and Withania somnifera are present in the composition in a weight ratio of about 6:2 Phyllanthus emblica to Withania somnifera to a weight ratio of about 3:5 Phyllanthus emblica to Withania somnifera. 15. The method according to claim 12, wherein the Phyllanthus emblica and Withania somnifera are present in the composition in a weight ratio of about 6:2 Phyllanthus emblica to Withania somnifera to a weight ratio of about 2:2 Phyllanthus emblica to Withania somnifera. 16. The method according to claim 12, wherein the Phyllanthus emblica and Withania somnifera are present in the composition in a weight ratio of about 5:3. 17. The method according to claim 12, wherein the composition comprises about 60 wt. % Withania somnifera to about 65 wt. % Withania somnifera and about 35 wt. % Phyllanthus emblica to about 40 wt. % Phyllanthus emblica. 18. The method according to claim 12, wherein the combination synergistically inhibits collagenases when consumed by the human. 19. The method according to claim 12, wherein the combination synergistically inhibits hyaluronidase activity when consumed by the human.

Details for Patent 8,329,231

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bausch & Lomb Incorporated	VITRASE	hyaluronidase	Injection	021640	05/05/2004	⤷ Try a Trial	2028-10-22
Bausch & Lomb Incorporated	VITRASE	hyaluronidase	Injection	021640	12/02/2004	⤷ Try a Trial	2028-10-22
Amphastar Pharmaceuticals, Inc.	AMPHADASE	hyaluronidase	Injection	021665	10/26/2004	⤷ Try a Trial	2028-10-22
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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