You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: May 10, 2024

Claims for Patent: 7,968,520

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 7,968,520

Title:	Chimeric DRG11-responsive (DRAGON) polypetides
Abstract:	This invention features methods and compositions useful for treating and diseases caused by a dysregulation of the BMP/GDF branch of the TGF-.beta. signaling pathway. Also disclosed are methods for identifying compounds useful for such therapy.
Inventor(s):	Woolf; Clifford J. (Newton, MA), Samad; Tarek A. (Gullford, CT)
Assignee:	The General Hospital Corporation (Boston, MA)
Application Number:	12/489,212
Patent Claims:	1. A composition comprising a chimeric polypeptide comprising a DRG11-Responsive (DRAGON) polypeptide and an Fc polypeptide, wherein the DRAGON polypeptide comprises the amino acid sequence of SEQ ID NO:1 or SEQ ID NO:2 without their C-terminal GPI domains. 2. The composition of claim 1, wherein the DRAGON polypeptide is a human DRAGON polypeptide. 3. The composition of claim 2, wherein the DRAGON polypeptide comprises the amino acid sequence of SEQ ID NO:2 without its C-terminal GPI domain. 4. The composition of claim 1, wherein the DRAGON fragment is a soluble DRAGON fragment. 5. The composition of claim 1, wherein the Fc polypeptide is derived from immunoglobulin G (IgG). 6. The composition of claim 1, further comprising a pharmaceutically acceptable carrier or salt. 7. The composition of claim 1, wherein the DRAGON polypeptide is a mouse DRAGON polypeptide. 8. The composition of claim 7, wherein the DRAGON polypeptide comprises the amino acid sequence of SEQ ID NO:1 without its C-terminal GPI domain.

Details for Patent 7,968,520

Glossary

Subscribe to access the full database, or Try a Trial
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Octapharma Pharmazeutika Produktionsges.m.b.h.	CUTAQUIG	immune globulin subcutaneous (human)-hipp	Solution	125668	12/12/2018	⤷ Try a Trial	2024-08-02
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.