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Last Updated: December 17, 2025

Claims for Patent: 7,923,221

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Summary for Patent: 7,923,221

Title:	Methods of making antibody heavy and light chains having specificity for a desired antigen
Abstract:	The invention relates to processes for producing an immunoglobulin or an immunologically functional immunoglobulin fragment containing at least the variable domains of the immunoglobulin heavy and light chains. The processes can use one or more vectors which produce both the heavy and light chains or fragments thereof in a single cell. The invention also relates to the vectors used to produce the immunoglobulin or fragment, and to cells transformed with the vectors.
Inventor(s):	Shmuel Cabilly, Herbert L. Heyneker, William E. Holmes, Arthur D. Riggs, Ronald B. Wetzel
Assignee:	Genentech Inc , City of Hope
Application Number:	US08/422,187

Details for Patent 7,923,221

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genzyme Corporation	CAMPATH	alemtuzumab	Injection	103948	May 07, 2001	7,923,221	2028-04-12
Genzyme Corporation	LEMTRADA	alemtuzumab	Injection	103948	November 14, 2014	7,923,221	2028-04-12
Genzyme Corporation	CAMPATH	alemtuzumab	Injection	103948	October 12, 2004	7,923,221	2028-04-12
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 7,923,221

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Country	Patent Number	Estimated Expiration
South Africa	842583	⤷ Get Started Free
United States of America	6331415	⤷ Get Started Free
United States of America	4816567	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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