Claims for Patent: 7,723,313
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Summary for Patent: 7,723,313
| Title: | Methods and compositions for inhibiting angiogenesis |
| Abstract: | The present invention provides a method of inhibiting angiogenesis within a tissue by providing exogenous PEDF to cells associated with the tissue. The presence of exogenous PEDF inhibits angiogenesis within the tissue, in part by interfering with the ability of vascular endothelia to expand within the tissue. The invention also provides a method for determining the severity of a tumor be assaying for the presence of PEDF within the tumor. To facilitate the inventive methods, the present invention provides pharmaceutical compositions including sources of PEDF. |
| Inventor(s): | Noel P. Bouck, David W. Dawson, Paul R. Gillis, Olga Volpert, Susan E. Crawford, Veronica M. Stellmach |
| Assignee: | Northwestern University |
| Application Number: | US11/494,363 |
Details for Patent 7,723,313
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Mannkind Corporation | AFREZZA | insulin human | Powder | 022472 | June 27, 2014 | 7,723,313 | 2026-07-26 |
| Mannkind Corporation | AFREZZA | insulin human | Powder | 022472 | April 17, 2015 | 7,723,313 | 2026-07-26 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
International Patent Family for US Patent 7,723,313
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| Austria | E413185 | ⤷ Start Trial |
| Australia | 3985501 | ⤷ Start Trial |
| Australia | 741886 | ⤷ Start Trial |
| Australia | 8509098 | ⤷ Start Trial |
| Canada | 2298018 | ⤷ Start Trial |
| Canada | 2401096 | ⤷ Start Trial |
| Canada | 2410699 | ⤷ Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
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