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Last Updated: April 19, 2024

Claims for Patent: 7,449,192

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Summary for Patent: 7,449,192

Title:	Use of neurotoxin therapy for treatment of urologic and related disorders related to neurogenic bladder dysfunction
Abstract:	The present invention related to methods for treating neurological-urological conditions, including neurogenic bladder dysfunction. This is accomplished by administration of a botulinum toxin into the lower urinary tract of a patient with a neurogenic bladder dysfunction, including the bladder or urinary sphincter and the bladder wall.
Inventor(s):	Schmidt; Richard A. (Arvada, CO)
Assignee:	The Regents of the University of Colorado (Denver, CO)
Application Number:	10/778,924
Patent Claims:	1. A method for treating a patient with a neurogenic bladder dysfunction, said method comprising the step of injecting a therapeutically effective amount of botulinum toxin type A into the lateral bladder wall of a patient with said neurogenic bladder dysfunction, thereby treating a symptom of said neurogenic bladder dysfunction. 2. The method of claim 1, wherein said neurogenic bladder dysfunction is secondary to a disease condition selected from the group consisting of Parkinson's disease, a spinal cord injury, a stroke, multiple sclerosis, and a spasm reflex. 3. The method of claim 1, wherein the step of injection comprises a single injection. 4. The method of claim 1, wherein the step of injection comprises injecting a gel comprising the botulinum toxin. 5. The method of claim 1, wherein the step of injecting results in increased bladder capacity. 6. The method of claim 1, wherein the therapeutically effective amount of botulinum toxin type A is up to 2500 units. 7. The method of claim 1, wherein the therapeutically effective amount of botulinum toxin type A is about 1.4 IU/kg to 17.1 IU/kg of botulinum toxin type A. 8. The method of claim 1, wherein the therapeutically effective amount of botulinum toxin type A is 200 IU of botulinum toxin type A.

Details for Patent 7,449,192

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Allergan, Inc.	BOTOX COSMETIC	onabotulinumtoxina	For Injection	103000	12/09/1991	⤷ Try a Trial	2017-07-15
Allergan, Inc.	BOTOX	onabotulinumtoxina	For Injection	103000	12/09/1991	⤷ Try a Trial	2017-07-15
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 7,449,192

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Country	Patent Number	Estimated Expiration
Austria	314085	⤷ Try a Trial
Austria	320815	⤷ Try a Trial
Austria	339220	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration

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