Claims for Patent: 7,371,928

Summary for Patent: 7,371,928

Title:	Plant seed-specific expression promoter derived from sesame and seed-specific expression vector comprising the promoter
Abstract:	Provided are a seed-specific expression promoter derived from sesame microsomal oleic acid desaturase (Si-FAD2) gene, an intron for expression enhancement, a seed-specific expression vector including the promoter and/or the intron, and a transgenic plant transformed with the seed-specific expression vector. Therefore, a useful product can be produced in a seed-specific manner or a common product in a seed can be functionally modified. Also, the promoter can be used together with the intron for expression enhancement, thereby increasing the expression level of an inserted gene in a seed. Therefore, it is very useful in development of a transgenic plant which induces large-scale expression of a foreign gene in a seed-specific manner.
Inventor(s):	Suh; Mi-Chung (Seoul, KR), Kim; Mi-Jung (Seoul, KR), Kim; Hee-Ja (Seoul, KR), Chung; Chung-Han (Busan, KR), Pyee; Jae-Ho (Gunpo, KR), Hyung; Nam-In (Cheonan, KR)
Assignee:	Korea Chungang Educational Foundation (Seoul, KR)
Application Number:	10/534,128
Patent Claims:	1. An isolated seed-specific promoter comprising SEQ ID NO: 3 or an active fragment thereof. 2. The seed-specific expression promoter of claim 1, which comprises the nucleotide sequence as set forth in SEQ ID NO: 3. 3. A seed-specific expression vector comprising the promoter of claim 1. 4. The seed-specific expression vector of claim 3, which is constructed by inserting the promoter upstream of a foreign gene of a binary vector. 5. The seed-specific expression vector of claim 4, wherein said foreign gene encodes a FAD2. 6. The seed-specific expression vector of claim 3, which is constructed by inserting the promoter upstream of a foreign gene of a transient expression vector. 7. The seed-specific expression vector of claim 6, wherein said foreign gene encodes a FAD2. 8. A transgenic plant transformed with the seed-specific expression vector of claim 3. 9. A method for expressing a foreign gene in a transgenic plant transformed with the seed-specific expression vector of claim 3. 10. The seed-specific expression vector of claim 3, which further comprises an intron for enhancement of gene expression comprising nucleotides 149 to 1722 of SEQ ID NO. 1.

Details for Patent 7,371,928

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986		2022-11-11
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132			2022-11-11
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132			2022-11-11