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Last Updated: April 26, 2024

Claims for Patent: 7,323,301

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Summary for Patent: 7,323,301

Title:	Nucleic acid, probe comprising the nucleic acid and screening method using the probe
Abstract:	A nucleic acid is (a) a nucleic acid comprising a base sequence shown in base numbers 1 39726 of SEQ ID NO: 1, or (b) a nucleic acid wherein a part of the bases 1 39726 of SEQ ID NO: 1 is deleted, substituted or added, and having a homology of 80% for the base sequence. Also, a probe comprises the above nucleic acid, and a screening is carried out by using such a probe.
Inventor(s):	Matsumoto; Naomichi (Nagasaki, JP), Niikawa; Norio (Nagasaki, JP)
Assignee:	Nagasaki University (Nagasaki, JP)
Application Number:	10/309,933
Patent Claims:	1. A screening method for diagnosing Sotos Syndrome comprising contacting a probe with a sample which is being evaluated for indication of Sotos Syndrome, said probe being derived from a genomic DNA sequence including an exon 1, an exon 2 and an intron of NSD1; (a) a nucleic acid comprising a base sequence shown in base numbers 1 39726 of SEQ ID NO: 1, or (b) a modified nucleic acid wherein a part of the bases 1 39726 of SEQ ID NO: 1 has been deleted or substituted, or to which at least one base has been added, said modified nucleic acid having a homology of 80% for said base sequence shown in base numbers 1 39726 of SEQ ID NO: 1. 2. The method according to claim 1, wherein the screening is carried out by using at least one selected from the group consisting of in situ hybridization method, Southern blotting method, and a base sequence determination method. 3. The method according to claim 2, wherein the in situ hybridization method is a fluorescence in situ hybridization method.

Details for Patent 7,323,301

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2021-12-19
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2021-12-19
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2021-12-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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