Claims for Patent: 7,186,820

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Summary for Patent: 7,186,820

Title:	Production of humanised antibodies to TNFα
Abstract:	There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNFα. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNFα.
Inventor(s):	Diljeet Singh Athwal, Derek Thomas Brown, Andrew Neil Charles Weir, Andrew George Popplewell, Andrew Paul Chapman, David John King
Assignee:	UCB SA , Celltech R&D Ltd
Application Number:	US09/949,559

Details for Patent 7,186,820

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Ucb, Inc.	CIMZIA	certolizumab pegol	For Injection	125160	April 22, 2008	7,186,820	2021-09-10
Ucb, Inc.	CIMZIA	certolizumab pegol	Injection	125160	March 28, 2019	7,186,820	2021-09-10
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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