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Last Updated: April 25, 2024

Claims for Patent: 6,956,022


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Summary for Patent: 6,956,022
Title: Agents for preventing and treating thrombocytopenia
Abstract:Method of increasing blood platelet formation by administering a parathyroid hormone (PTH) or at least one PTH derivative as an active ingredient.
Inventor(s): Tamura; Masahiko (Shizuoka-ken, JP), Oda; Yasuhiro (Nagano-ken, JP)
Assignee: Chugai Seiyaku Kabushiki Kaisha (Tokyo, JP)
Application Number:10/026,696
Patent Claims:1. A method for increasing platelet count in a patient in need thereof, comprising administering to said patient an effective amount of a composition comprising a parathyroid hormone (PTH) or a derivative thereof.

2. The method according to claim 1 wherein said PTH or PTH derivative modified with polyethylene glycol is administered.

3. The method according to claim 1 wherein said PTH or PTH derivative is administered encapsulated within microcapsules.

4. The method according to claim 1 wherein said PTH or PTH derivative is incorporated in a sheet of gel.

5. The method according to claim 1 wherein said effective amount is in the range of 1 .mu.g to 1,000 .mu.g per kg of body weight administered systemically at a frequency ranging from once per day to once per month.

6. The method according to claim 1 wherein said effective amount is from 5 .mu.g to 200 .mu.g per kg of body weight administered from once every two weeks to once daily.

7. The method according to claim 1 wherein the route of said administration is subcutaneously.

8. The method according to claim 1 wherein the route of said administration is intravenously.

9. The method according to claim 1 wherein the route of said administration is intranasally.

10. The method according to claim 1 wherein the route of said administration is transpulmonarily.

11. The method of claim 1, wherein said PTH or PTH derivative is human PTH (1-34).

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