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Last Updated: April 26, 2024

Claims for Patent: 6,821,520

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Summary for Patent: 6,821,520

Title:	Clostridial toxin therapy for Hashimoto\'s thyroiditis
Abstract:	Methods for treating the hypothyroidism of Hashimoto\'s thyroiditis by local administration of a Clostridial toxin, such as a botulinum toxin, to the thyroid gland of a patient.
Inventor(s):	Voet; Martin A. (San Juan Capistrano, CA), Donovan; Stephen (Capistrano Beach, CA)
Assignee:	Allergan, Inc. (Irvine, CA)
Application Number:	10/099,238
Patent Claims:	1. A method for treating Hashimoto's thyroiditis, the method comprising the step of local administration of a therapeuticlly effective amount of a botulinum toxin to a patient, thereby treating Hashimoto's thyroiditis by alleviating a symptom of Hashimoto's thyroiditis selected from the group of symptoms consisting of hypothyroidism, goiter and thyroid follicular hyperlasia. 2. The method of claim 1, wherein the botulinum toxin is locally administered to the thyroid gland of the patient. 3. The method of claim 1, wherein the botulinum toxin is selected from the group consisting of botulinum toxin types A, B, C, D, E, F and G. 4. The method of claim 1, wherein the botulinum toxin is botulinumtoxin type A. 5. The method of claim 2, wherein the botulinum toxin is administered to the thyroid gland of the patient by placement of a botulinum toxin implant on or in the thyroid gland. 6. A method for treating Hashimoto's thyroiditis, the method comprising the step of administration of a therapeutically effective amount of a botulinum toxin to a thyroid gland of a patient by direct injection of the botulinum toxin into the thyroid gland, thereby treating Hashimoto's thyroiditis by alleviating a symptom of Hashimoto's thyroiditis selected from th group of symptoms consisting of hypothyroidism, goiter and thyroid follicular hyperplasia. 7. The method of claim 6, wherein the botulinum toxin is selected from the group consisting of botulinum toxin types A, B, C, D, E, F and G. 8. The method of claim 7, wherein the botulinum toxin is botulinum toxin type A. 9. The method of claim 7, wherein the botulinum toxin is botulinum toxin type B. 10. A method for amelioration of Hashimoto's thyroiditis, the method comprising the step of local administration of a therapeuticall effective amount of a botulinum toxin type A to a patient, by direct injection of the botulinum toxin into the thyroid gland, thereby treating Hashimoto's thyroiditis by alleviating a symptom of Hashimoto's thyroiditis selected from the group of symptoms consisting of hypothyroidism goiter an thyroid follicular hyperplasia.

Details for Patent 6,821,520

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Solstice Neurosciences, Llc	MYOBLOC	rimabotulinumtoxinb	Injection	103846	12/08/2000	⤷ Try a Trial	2020-02-15
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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