You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: April 26, 2024

Claims for Patent: 6,440,719

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 6,440,719

Title:	Method and reagent for inhibiting herpes simplex virus replication
Abstract:	An enzymatic RNA molecule which specifically cleaves a herpes simplex virus mRNA molecule.
Inventor(s):	Draper; Kenneth G. (Boulder, CO)
Assignee:	Ribozyme Pharmaceuticals, Inc. (Boulder, CO)
Application Number:	09/634,262
Patent Claims:	1. An enzymatic RNA molecule which cleaves RNA encoded by a herpes simplex virus (HSV) in a gene selected from ICP4, and UL5. 2. The enzymatic RNA molecule of claim 1, wherein said RNA molecule is in a hammerhead motif. 3. The enzymatic RNA molecule of claim 1, wherein said RNA molecule is in a hairpin, hepatitis Delta virus, group 1 intron, or RNAseP RNA motif. 4. The enzymatic RNA molecule of claim 1 which cleaves the sequence shown as any of SEQ. ID. NOS. 1-115. 5. An isolated mammalian cell including an enzymatic RNA molecule of claim 1. 6. The cell of claim 5, wherein said cell is a human cell. 7. An expression vectors including nucleic acid encoding the enzymatic RNA molecule of claim 1. 8. A method of treating HSV by administering the enzymatic RNA molecule of claim 2. 9. The method of claim 8, wherein said molecule is active to cleave mRNA required for viral protein synthesis. 10. A method for treating a cell infected with latent HSV comprising the step of contacting an enzymatic RNA molecule of claim 1 with said infected cell. 11. A method for treating a cell infected with latent HSV comprising the step of contacting an enzymatic RNA molecule which is active to specifically cleave RNA encoded by a herpes simplex virus (HSV) in a gene selected from ICP4 and UL5 with said infected cell.

Details for Patent 6,440,719

Glossary

Subscribe to access the full database, or Try a Trial
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2012-05-14
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2012-05-14
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2012-05-14
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.