Claims for Patent: 6,429,259

Summary for Patent: 6,429,259

Title:	Water soluble polymeric complex comprising a conducting polymer and a biopolymer
Abstract:	A molecular complex which comprises a biopolymer having a plurality of ionic functional groups and a conductive polymer having charges therein. The charges bind to the ionic functional groups to form the complex. The conductive polymer is selected from the group consisting essentially of polyaniline, polypyrrole, polythiophene, poly(phenylenevinylene) or poly(phenylene sulfide) and substituted versions thereof.
Inventor(s):	Yang; Sze Cheng (Wakefield, RI), McCarthy; Patrick (Oakland, CA)
Assignee:	The Board of Governors for Higher Education, State of Rhode Island and (N/A) (Providence, RI)
Application Number:	09/825,074
Patent Claims:	1. A molecular complex which comprises: a biopolymer, having a plurality of ionic functional groups; and a conductive polymer having charges therein which bind to the ionic functional groups to form the complex. 2. The complex of claim 1 wherein: the biopolymer is selected from the group consisting essentially of proteins and nucleic acids. 3. The complex of claim 1 wherein: the proteins comprise albumins. 4. The complex of claim 3 wherein: the albumins are selected from the groups consisting essentially of bovine serum albumin or human serum albumin. 5. The complex of claim 1 or 4 wherein: the conductive polymer is selected from the group consisting of polyaniline, polypyrrole, polythiophene, poly(phenylenevinylene), poly(phenylene sulfide) and substituted versions thereof. 6. The complex of claim 5 wherein: the conductive polymer is either polyaniline or polypyrrole. 7. A method for the formation of a molecular complex: adding a conductive monomer to a biopolymer to form an adduct; the monomer attaching to the biopolymer polymerizing the monomer to form a conductive polymer the biopolymer and conductive polymer forming the molecular complex. 8. The method of claim 7 wherein: the monomer and biopolymer form a non-covalent adduct. 9. The method of claim 8 which comprises: acidifying the adduct. 10. The method of claim 9 which comprises: acidifying the adduct prior to polymerizing the adduct. 11. The method of claim 7 wherein: the molecular complex is a solution. 12. The method of claim 7 wherein: the biopolymer is selected from the group consisting of proteins and nucleic acids. 13. The method of claim 7 wherein: the proteins comprise albumins. 14. The method of claim 13 wherein: the albumins are selected from the groups consisting of bovine serum albumin and human serum albumin. 15. The methods of claim 7 or 14 wherein: the conductive polymer is selected from the group consisting of polyaniline, polypyrrole, polythiophene, poly(phenylenevinylene), poly(phenylene sulfide) and substituted versions thereof. 16. The method of claim 15 wherein: the conductive polymer is either polyaniline or polypyrrole.

Details for Patent 6,429,259

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Grifols Therapeutics Llc	ALBUKED, PLASBUMIN-20, PLASBUMIN-25, PLASBUMIN-5	albumin (human)	For Injection	101138	October 21, 1942	6,429,259	2021-04-03
Takeda Pharmaceuticals U.s.a., Inc.	BUMINATE, FLEXBUMIN	albumin (human)	Injection	101452	March 03, 1954	6,429,259	2021-04-03
Csl Behring Ag	ALBURX	albumin (human)	Injection	102366	July 23, 1976	6,429,259	2021-04-03