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Last Updated: April 18, 2024

Claims for Patent: 6,429,259


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Summary for Patent: 6,429,259
Title: Water soluble polymeric complex comprising a conducting polymer and a biopolymer
Abstract:A molecular complex which comprises a biopolymer having a plurality of ionic functional groups and a conductive polymer having charges therein. The charges bind to the ionic functional groups to form the complex. The conductive polymer is selected from the group consisting essentially of polyaniline, polypyrrole, polythiophene, poly(phenylenevinylene) or poly(phenylene sulfide) and substituted versions thereof.
Inventor(s): Yang; Sze Cheng (Wakefield, RI), McCarthy; Patrick (Oakland, CA)
Assignee: The Board of Governors for Higher Education, State of Rhode Island and (N/A) (Providence, RI)
Application Number:09/825,074
Patent Claims:1. A molecular complex which comprises: a biopolymer, having a plurality of ionic functional groups; and a conductive polymer having charges therein which bind to the ionic functional groups to form the complex.

2. The complex of claim 1 wherein: the biopolymer is selected from the group consisting essentially of proteins and nucleic acids.

3. The complex of claim 1 wherein: the proteins comprise albumins.

4. The complex of claim 3 wherein: the albumins are selected from the groups consisting essentially of bovine serum albumin or human serum albumin.

5. The complex of claim 1 or 4 wherein: the conductive polymer is selected from the group consisting of polyaniline, polypyrrole, polythiophene, poly(phenylenevinylene), poly(phenylene sulfide) and substituted versions thereof.

6. The complex of claim 5 wherein: the conductive polymer is either polyaniline or polypyrrole.

7. A method for the formation of a molecular complex: adding a conductive monomer to a biopolymer to form an adduct; the monomer attaching to the biopolymer polymerizing the monomer to form a conductive polymer the biopolymer and conductive polymer forming the molecular complex.

8. The method of claim 7 wherein: the monomer and biopolymer form a non-covalent adduct.

9. The method of claim 8 which comprises: acidifying the adduct.

10. The method of claim 9 which comprises: acidifying the adduct prior to polymerizing the adduct.

11. The method of claim 7 wherein: the molecular complex is a solution.

12. The method of claim 7 wherein: the biopolymer is selected from the group consisting of proteins and nucleic acids.

13. The method of claim 7 wherein: the proteins comprise albumins.

14. The method of claim 13 wherein: the albumins are selected from the groups consisting of bovine serum albumin and human serum albumin.

15. The methods of claim 7 or 14 wherein: the conductive polymer is selected from the group consisting of polyaniline, polypyrrole, polythiophene, poly(phenylenevinylene), poly(phenylene sulfide) and substituted versions thereof.

16. The method of claim 15 wherein: the conductive polymer is either polyaniline or polypyrrole.

Details for Patent 6,429,259

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Grifols Therapeutics Llc ALBUKED, PLASBUMIN-20, PLASBUMIN-25, PLASBUMIN-5 albumin (human) For Injection 101138 10/21/1942 ⤷  Try a Trial 2020-04-03
Baxalta Us Inc. BUMINATE, FLEXBUMIN albumin (human) Injection 101452 03/03/1954 ⤷  Try a Trial 2020-04-03
Csl Behring Ag ALBURX albumin (human) Injection 102366 07/23/1976 ⤷  Try a Trial 2020-04-03
Grifols Biologicals Llc ALBUTEIN albumin (human) Injection 102478 08/15/1978 ⤷  Try a Trial 2020-04-03
Instituto Grifols, S.a. HUMAN ALBUMIN GRIFOLS albumin (human) Injection 103352 02/17/1995 ⤷  Try a Trial 2020-04-03
Instituto Grifols, S.a. HUMAN ALBUMIN GRIFOLS albumin (human) Injection 103352 06/11/2003 ⤷  Try a Trial 2020-04-03
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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