You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: April 26, 2024

Claims for Patent: 6,015,713

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 6,015,713

Title:	Transgenic fish and a method of harvesting islet cells therefrom
Abstract:	This invention relates to transgenic fish containing a humanized insulin gene which has been altered to secrete human insulin and its use in the treatment of diabetes. In the transgenic fish of the present invention, the fish insulin gene has been modified to code for human insulin gene while leaving the regulatory sequences of fish insulin gene intact. Islet transplantation may provide the meticulous glycemia control required in the treatment of diabetes. The islet tissue of the present invention offers an inexpensive and a nearly unlimited supply of human insulin-producing tissue and therefore, may be useful in the treatment of diabetes. In this regard, an improved method of mass isolation of islet tissue is provided by the present invention. The present invention also provides the use of the humanized insulin gene to promote growth in fish.
Inventor(s):	Wright, Jr.; James R. (Halifax, CA), Pohajdak; Bill (Dartmouth, CA)
Assignee:	Dalhousie University (Nova Scotia, CA)
Application Number:	08/750,391
Patent Claims:	1. A method for harvesting principal islets from fish, said method comprising: a) incubating islet-containing tissue obtained from fish, wherein said islet-containing tissue comprises adipose tissue and connective tissue, with collagenase type II for a period of time sufficient to release the islets from adipose and connective tissue; and b) separating the released islets from said adipose and connective tissue. 2. The method according to claim 1 wherein, in step a), the islet-containing tissue is incubated with the collagenase at 37.degree. C. for about 10 to about 20 minutes.

Details for Patent 6,015,713

Glossary

Subscribe to access the full database, or Try a Trial
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965	⤷ Try a Trial	2015-04-06
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.