Last Updated: May 14, 2026

Claims for Patent: 5,965,530

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Summary for Patent: 5,965,530

Title:	Therapeutic uses of keratinocyte growth factor
Abstract:	Based on extensive in vivo studies in animals, it has now been discovered that KGF stimulates proliferation, growth and differentiation in various cells of epithelial tissue, besides keratinocytes. This better understanding of the biological effects of KGF in vivo enables the use of this polypeptide as a therapeutic agent, suitably formulated in a pharmaceutical composition, for the specific treatment of disease states and medical conditions afflicting tissues and organs such as the dermal adnexae, the liver, the lung, and the gastrointestinal tract.
Inventor(s):	Glenn Francis Pierce, Regina Mae Housley, Charles Frederick Morris
Assignee:	Swedish Orphan Biovitrum AB
Application Number:	US08/484,068

Details for Patent 5,965,530

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Swedish Orphan Biovitrum Ab (publ)	KEPIVANCE	palifermin	For Injection	125103	December 15, 2004	⤷ Start Trial	2016-10-12
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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