Claims for Patent: 5,817,794
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Summary for Patent: 5,817,794
Title: | Isolated DNA sequence comprising DNA encoding human cytoplasmic Cu-Zn superoxide dismutase |
Abstract: | Methods and compositions are provided for the production of human superoxide dismutase and a novel protocol for enhancing efficiency of expression. The gene encoding for human superoxide dismutase is isolated and inserted into a vector in conjunction with a synthetic linker which provides for enhanced efficiency in translation. |
Inventor(s): | Hallewell; Robert A. (San Francisco, CA), Mullenbach; Guy T. (Oakland, CA) |
Assignee: | Chiron Corporation (Emeryville, CA) |
Application Number: | 08/453,448 |
Patent Claims: | 1. The isolated DNA molecule comprising human genomic DNA encoding Cu/Zn cytoplasmic superoxide dismutase, wherein the 5' terminus of the DNA molecule comprises an intron,
and the intron comprises the sequence GCA AGG GCT GGG ACG GAG GCT TG.
2. The isolated DNA molecule of claim 1, wherein said DNA molecule comprises an insert in pS2OR. |
Details for Patent 5,817,794
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | 06/04/1986 | ⤷ Try a Trial | 2015-10-06 |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | ⤷ Try a Trial | 2015-10-06 | |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | Injection | 103132 | ⤷ Try a Trial | 2015-10-06 | |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
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