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Last Updated: December 18, 2025

Claims for Patent: 5,541,293

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Summary for Patent: 5,541,293

Title:	Consensus human leukocyte interferon
Abstract:	Disclosed are analogs of human leukocyte interferon which predominantly include those amino acid residues which are common to all naturally-occurring human leukocyte interferon subtype amino acid sequences and which include, at one or more of those positions where there is no amino acid common to all subtypes, an amino acid which predominantly occurs at that position and in no event include any amino acid residue which is not extant in that position in at least one naturally-occurring subtype.
Inventor(s):	Stabinsky; Yitzhak (Boulder, CO)
Assignee:	Amgen Inc. (Thousand Oaks, CA)
Application Number:	07/472,328
Patent Claims:	1. Consensus human leukocyte interferon. 2. A consensus human leukocyte interferon according to claim 1 selected from the group consisting of: [Thr.sup.14, Met.sup.16, Arg.sup.22, Ala.sup.76, Asp.sup.78, Glu.sup.79, Tyr.sup.86, Tyr.sup.90, Leu.sup.96, Thr.sup.156, Asn.sup.157, Leu.sup.158 ]IFN-.alpha.F; and [Arg.sup.22, Ala.sup.76, Asp.sup.78, Glu.sup.79, Tyr.sup.86, Tyr.sup.90, Leu.sup.96, Glu.sup.114, Arg.sup.121, Thr.sup.156, Asn.sup.157, Leu.sup.158 ]IFN-.alpha.F.

Details for Patent 5,541,293

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Kadmon Pharmaceuticals Llc	INFERGEN	interferon alfacon-1	Injection	103663	October 06, 1997	5,541,293	2010-01-30
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 5,541,293

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	8304053	⤷ Get Started Free
United States of America	RE39821	⤷ Get Started Free
United States of America	6936695	⤷ Get Started Free
United States of America	6936694	⤷ Get Started Free
United States of America	5661009	⤷ Get Started Free
United States of America	4897471	⤷ Get Started Free
United States of America	4695623	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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