Claims for Patent: 5,122,147

Summary for Patent: 5,122,147

Title:	Polyp marking device and method
Abstract:	Surgical method and instrument such as a snare or forceps clamps, which can be moved to a position to firmly grasp a polyp. A tissue marking agent is disposed on the surface of the instrument that contacts a polyp, and the marking agent is crushed against the polyp. The marking agent is absorbed by the polyp and stains the tissue from which the polyp projects, the assist in visualizing the polyp site if conventional surgery is later required. The method and device may optionally provide for cutting and removing of the polyp and for application of a hemostatic agent to the polyp base to minimize bleeding.
Inventor(s):	Sewell, Jr.; Frank K. (Henderson, KY)
Assignee:
Application Number:	07/681,091
Patent Claims:	1. A surgical polyp marking snare comprising: a housing, a first wire loop extending from the housing, a crushable tissue marking agent disposed on the wire loop, the wire loop being movable between an extended position in which the loop may be placed over a polyp, and a retracted position in which the size of the loop is reduced to thereby crush the marking agent against the polyp, and means to move the wire loop between the extended and retracted positions. 2. The surgical polyp marking snare of claim 1 wherein the tissue marking agent comprises carbon granules. 3. The surgical polyp marking snare of claim 1 wherein the tissue marking agent comprises a solid crushable capsule shell with a liquid marking dye within the shell. 4. The surgical polyp marking snare of claim 1 wherein a first portion of the loop is fixed with respect to the housing and a second portion of the loop is movable with respect to the housing, the tissue marking agent being disposed on the wire loop between the fixed and movable portions, and wherein the loop is movable between the extended and retracted positions by moving the movable portion toward the housing. 5. The surgical polyp marking snare of claim 1 further comprising first and second sides of the wire loop, the tissue marking agent being disposed on the wire loop between the first and second sides, the loop being movable from the extended to the retracted position by simultaneously pulling the first and second sides toward the housing. 6. The surgical polyp marking snare of claim 1 wherein the tissue marking agent is disposed in a recess in the first wire loop. 7. The surgical polyp marking snare of claim 1 wherein the wire loop is metal. 8. The surgical polyp marking snare of claim 1 further comprising a topical hemostatic agent disposed on the wire loop, such that the hemostatic agent may contact a polyp when the wire loop is moved against the polyp. 9. The surgical polyp marking snare of claim 8 wherein the topical hemostatic agent is selected from the group consisting of denatured animal gelatin, topical thrombin, epinephrine, oxidized regenerated cellulose, microfibrillar collagen or modified collagen hemin comprising calcium fluoride. 10. The surgical polyp marking snare of claim 1 further comprising a structure having an aperture, the first loop passing through the aperture, a plurality of wedges extending from the first loop, such that when the first loop is moved towards its retracted position, the wedges ratchetedly pass through the aperture to thereby restrict movement of the first loop toward the extended position. 11. The surgical polyp marking snare of claim 1 further comprising: a second cutting wire loop adjacent to the first wire loop such that both loops may be simultaneously placed over a polyp, the second wire loop being movable between extended and retracted positions, such that when the second loop is moved toward its retracted position it may sever the polyp. 12. The surgical polyp marking snare of claim 11, wherein the second cutting wire loop traverses the first wire loop, such that the second cutting wire loop may sever the first wire loop when moved towards its retracted position. 13. The surgical polyp marking snare of claim 11, further comprising a third wire loop adjacent to the second wire loop and on the side of the second wire loop opposite the first wire loop, the third wire loop being movable between extended and retracted positions, the third wire loop comprising at least one inwardly projecting polyp holding means. 14. The surgical polyp marking snare of claim 13 further comprising at least one spacing member having three apertures, the first, second and third loops passing through one respective aperture to thereby space the loops apart from each other. 15. The surgical polyp marking snare of claim 13 wherein the first loop is comprised of metal, and the second and third loops are comprised of a material selected from the group of polymeric silicone or plastic. 16. A surgical polyp marking forceps comprising: a pair of opposing jaws adapted to close an anatomical structure therebetween, the jaws being insertable into a human colon, means to close the jaws, a crushable tissue marking agent disposed on at least one of the jaws and a marking agent crushing means on the opposite jaw, such that the crushing means crushes the marking agent when the jaws are closed. 17. The surgical polyp marking forceps of claim 16 further comprising upper and lower opposing blades adjacent to the jaws, such that tissue between the blades is cut when the jaws are closed. 18. The surgical polyp marking forceps of claim 16 further comprising first and second ends of the jaws, and a blade adjacent the jaws movable between from the first jaw end toward the second jaw end to thereby cut tissue located between the ends. 19. The surgical polyp marking forceps of claim 16 wherein the tissue marking agent comprises carbon granules. 20. The surgical polyp marking forceps of claim 16 wherein the tissue marking agent comprises a solid crushable capsule shell with a liquid marking dye within the shell. 21. The surgical polyp marking forceps of claim 16 further comprising a topical hemostatic agent disposed on at least one of the jaws, such that the hemostatic agent may contact a polyp when the jaws are closed. 22. The surgical polyp marking snare of claim 21 wherein the topical hemostatic agent is selected from the group consisting of denatured animal gelatin, topical thrombin, epinephrine, oxidized regenerated cellulose, microfibrillar collagen or modified collagen hemin comprising calcium fluoride. 23. A method for marking a polyp, comprising the steps of: providing a device for crushing a crushable tissue marking agent against the polyp, crushing the tissue marking agent against the polyp, and holding the crushed tissue marking agent against the polyp until the marking agent is lymphatically absorbed by the polyp and carried to the base of the polyp. 24. The method of claim 23 wherein the crushing device comprises a snare. 25. The method of claim 23 wherein the crushing device comprises a forceps clamp. 26. The method of claim 23 wherein the tissue marking agent comprises carbon granules. 27. The method of claim 23 wherein the tissue marking agent comprises a solid crushable capsule shell with a liquid marking dye within the shell. 28. The method of claim 23 further comprising the step of severing the polyp from the tissue from which it projects. 29. The method of claim 23 further comprising the step of applying a topical hemostatic agent to the polyp. 30. The method of claim 29 wherein the topical hemostatic agent is selected from the group consisting of denatured animal gelatin, topical thrombin, epinephrine, oxidized regenerated cellulose, microfibrillar collagen or modified collagen hemin comprising calcium fluoride.

Details for Patent 5,122,147

Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Recordati Rare Diseases, Inc.	PANHEMATIN	hemin for injection	For Injection	101246	07/20/1983		2040-01-28