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Generated: August 20, 2019

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Claims for Patent: 4,959,210

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Summary for Patent: 4,959,210
Title: Treatment of genital warts with a combination of liquid nitrogen and recombinant DNA human alpha interferon
Abstract:Condylomata Acuminata infections (anogenital warts) are treated in infected patients by administering liquid nitrogen and immediately thereafter beginning administering recombinant DNA human alpha interferon thrice a week for three weeks. The interferon exemplified is recombinant DNA human interferon alfa-2b in which 1.0.times.10.sup.6 International Units are administered by injection to each lesion. The liquid nitrogen is the cryosurgical agent exemplified and it is topically administered to each lesion by conventional means.
Inventor(s): Smiles; Kenneth A. (Windsor, NJ), Peets; Edwin A. (New York, NY), Tanner; Daniel J. (Brooklyn, NY)
Assignee: Schering Corporation (Kenilworth, NJ)
Application Number:07/265,612
Patent Claims:1. A method of treating condylomata acuminata infections in patients in need of such treatment comprising administering to each lesion an effective amount of a cryosurgical agent, followed by administration to each lesion immediately thereafter an effective amount of human alpha interferon.

2. A method of claim 1 wherein the cryosurgical agent is liquid nitrogen.

3. A method of claim 1 wherein the human alpha interferon is recombinant human DNA interferon alfa-2b.

4. A method of claim 1 wherein the human alpha interferon is recombinant human DNA interferon alfa-2a.

5. A method of claim 1 wherein the treatment is sufficiently frequent and for a sufficient length of time to be efficacious.

6. A method of claim 1 wherein the treatment with said interferon is thrice a week for three weeks.

7. A method of claim 3 wherein the treatment with said interferon is thrice a week for three weeks.

8. A method of claim 4 wherein the treatment with said interferon is thrice a week for three weeks.

9. A method of claim 1 wherein the human alpha interferon is administered by intralesional injection and the liquid nitrogen is administered topically.

10. A method of claim 9 wherein the human alpha interferon is recombinant human DNA interferon alfa-2b.

Details for Patent 4,959,210

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04 ➤ Sign Up Schering Corporation (Kenilworth, NJ) 2036-04-30 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04 ➤ Sign Up Schering Corporation (Kenilworth, NJ) 2036-04-30 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04 ➤ Sign Up Schering Corporation (Kenilworth, NJ) 2036-04-30 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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